{"id":"W2769546449","doi":"10.3899/jrheum.170266","title":"Plasma MicroRNA Profiles in Patients with Early Rheumatoid Arthritis Responding to Adalimumab plus Methotrexate vs Methotrexate Alone: A Placebo-controlled Clinical Trial","year":2017,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Rigshospitalet; Gentofte Hospital; European League Against Rheumatism; Gigtforeningen","keywords":"Medicine; Methotrexate; Rheumatoid arthritis; Adalimumab; Placebo; Internal medicine; Arthritis; Clinical trial; Antirheumatic Agents; Oncology; Immunology; Gastroenterology; Pathology; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001781419,0.001285482,0.003280294,0.00030814,0.0003403494,0.0008756187,0.0005643438,0.001378393,0.002284094],"category_scores_gemma":[0.001478687,0.000490893,0.001478931,0.0002892803,0.0006852324,0.0005959728,0.0002909207,0.001466588,0.0004322753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003328847,"about_ca_system_score_gemma":0.000429662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001588898,"about_ca_topic_score_gemma":0.0003609486,"domain_scores_codex":[0.9992287,0.0003914224,0.0000675173,0.0001855374,0.00006448699,0.00006233483],"domain_scores_gemma":[0.9990628,0.0002861692,0.0003262261,0.00006524988,0.00005683905,0.0002026882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9766012,0.00441074,0.003424776,0.0004635958,0.001084517,0.00003500865,0.00003117653,0.0001642417,0.003955857,0.00002280804,0.0001171001,0.009688948],"study_design_scores_gemma":[0.7678639,0.2068667,0.01987568,0.00006102248,0.00236894,0.00009618521,0.00003436563,0.001009065,0.001087685,0.0001387208,0.0005694295,0.00002822645],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943088,0.004155391,0.0002489495,0.0001356536,0.0001416765,0.0004667403,0.0001818018,0.00002781485,0.0003332812],"genre_scores_gemma":[0.996379,0.001006599,0.0005360614,0.000292737,0.000260389,0.0007502869,0.0002762687,0.000005559978,0.0004931618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003280294,"threshold_uncertainty_score":0.00942117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02810265004015778,"score_gpt":0.3350644847052345,"score_spread":0.3069618346650768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}