{"id":"W2769932926","doi":"10.1152/ajprenal.00445.2017","title":"Dapagliflozin in focal segmental glomerulosclerosis: a combined human-rodent pilot study","year":2017,"lang":"en","type":"article","venue":"American Journal of Physiology-Renal Physiology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital; University of Manitoba; St. Michael's Hospital; Sunnybrook Health Science Centre; University Health Network; University of Toronto; Health Sciences Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Banting and Best Diabetes Centre, University of Toronto; Kidney Foundation of Canada; Canadian Diabetes Association","keywords":"Renal function; Medicine; Proteinuria; Urology; Internal medicine; Endocrinology; Kidney disease; Glomerulosclerosis; Effective renal plasma flow; Focal segmental glomerulosclerosis; Albuminuria; Kidney; Nephropathy; Renal blood flow; Excretion; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001932941,0.001054344,0.001905593,0.0007826601,0.0004037201,0.0006316144,0.0007928126,0.0009398933,0.002340998],"category_scores_gemma":[0.0004160049,0.0004259619,0.001144428,0.0004339861,0.00107047,0.0008849242,0.0004382231,0.001912037,0.0003359962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005818964,"about_ca_system_score_gemma":0.0008586392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001078274,"about_ca_topic_score_gemma":0.00168597,"domain_scores_codex":[0.999426,0.0001697441,0.00004905177,0.0001339652,0.00008305008,0.000138161],"domain_scores_gemma":[0.9994868,0.00005756167,0.00008349765,0.0001062083,0.00004360832,0.000222263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.1475799,0.0984662,0.005165118,0.00131469,0.001220957,0.0008816526,0.0002183672,0.001102215,0.6697506,0.0006142226,0.002407293,0.07127882],"study_design_scores_gemma":[0.03459936,0.7831426,0.02459578,0.00009366965,0.002209611,0.001343834,0.0002252167,0.0023682,0.139765,0.0002570059,0.01130962,0.00009013587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936146,0.002637913,0.001447954,0.0002649716,0.0001325131,0.0005845998,0.0004940305,0.0001162666,0.0007071017],"genre_scores_gemma":[0.9892159,0.003692613,0.002469476,0.000351312,0.0001392728,0.0009595825,0.001270464,0.00002383355,0.001877593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002340998,"threshold_uncertainty_score":0.01022243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02976761704707564,"score_gpt":0.3085535524859855,"score_spread":0.2787859354389099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}