{"id":"W2769977504","doi":"10.1021/jacs.7b07047","title":"Fluorogenic Targeting of Voltage-Sensitive Dyes to Neurons","year":2017,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; UC Berkeley College of Chemistry; National Institutes of Health; Agency for Science, Technology and Research; University of California Berkeley; Esther A. and Joseph Klingenstein Fund; Simons Foundation; Alfred P. Sloan Foundation","keywords":"Chemistry; Fluorescence; Enzyme; Biophysics; Neuron; Biochemistry; In vitro; Cell; Neuroscience; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003081362,0.0001000786,0.0002766318,0.0000158403,0.0002531867,0.00005363364,0.001196612,0.00002712659,0.00001566062],"category_scores_gemma":[0.002613019,0.00006608594,0.0005025978,0.0001730132,0.0008518343,0.00007225326,0.0005102642,0.000398383,0.000004898084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006975532,"about_ca_system_score_gemma":0.00009003484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003144555,"about_ca_topic_score_gemma":3.406029e-7,"domain_scores_codex":[0.9986405,0.00007339258,0.0002861635,0.0001587436,0.0005684842,0.000272664],"domain_scores_gemma":[0.9983218,0.0002768241,0.0007175317,0.0003575198,0.0001551107,0.000171237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004712593,0.00004209319,0.001718703,0.000004276898,0.00001560742,0.000002607683,0.0002825521,0.00001362232,0.9927235,0.000005627697,0.003822916,0.001321334],"study_design_scores_gemma":[0.0001452213,0.00009030612,0.004103416,0.00001635709,0.0000135613,0.00001858807,0.0001608391,0.000161169,0.9940398,0.00005983728,0.001119843,0.00007109001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981008,0.00001360435,0.0001037692,0.001269283,0.0001599453,0.00007709365,0.00001420594,0.000004009443,0.0002572648],"genre_scores_gemma":[0.9977594,0.00008026589,0.001083048,0.0008172704,0.0001863779,9.712139e-7,6.66013e-8,0.00001377004,0.00005881277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002703073,"threshold_uncertainty_score":0.3138619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03166450546843428,"score_gpt":0.3281774664413179,"score_spread":0.2965129609728836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}