{"id":"W2770169340","doi":"10.2147/cmar.s147326","title":"Checkpoint blockade in solid tumors and B-cell malignancies, with special consideration of the role of CD200","year":2017,"lang":"en","type":"review","venue":"Cancer Management and Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Blockade; Immune checkpoint; Cancer research; Cancer; Immune system; Immunology; Biology; Medicine; Immunotherapy; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001376057,0.0002662227,0.0003783382,0.0004203978,0.0001084264,0.000352187,0.0002619315,0.0003376851,0.001172802],"category_scores_gemma":[0.0001336106,0.00004581028,0.0001941224,0.0003729794,0.0001446301,0.0003185066,0.0002265188,0.0005873974,0.0004472919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002147311,"about_ca_system_score_gemma":0.0002591108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002330859,"about_ca_topic_score_gemma":0.0006426343,"domain_scores_codex":[0.9999433,0.00001002649,0.000007136786,0.00001026152,0.00002061513,0.000008671734],"domain_scores_gemma":[0.9999577,0.0000194,0.000009860007,0.000001876965,0.000005869089,0.000005336105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001618564,0.00008510789,0.000296454,0.006689005,0.00005998439,0.0003463654,0.00005120095,0.0004251511,0.02712252,0.002823867,0.008778719,0.9531597],"study_design_scores_gemma":[0.00006862423,0.001230869,0.003125005,0.001280059,0.0001936144,0.005231031,0.00008762504,0.000284234,0.01896863,0.003099926,0.9664088,0.00002162036],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003529821,0.9922651,0.0007103686,0.0003903484,0.0001990724,0.00001294004,0.00003075048,0.0000286355,0.002833061],"genre_scores_gemma":[0.02098698,0.9748813,0.0009047788,0.0004919047,0.00039125,0.00002093585,0.0001099956,0.000005519644,0.00220735],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001172802,"threshold_uncertainty_score":0.003923416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09535184495420482,"score_gpt":0.4029308205727563,"score_spread":0.3075789756185515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}