{"id":"W2770186014","doi":"10.1194/jlr.m080028","title":"Genomic and lipidomic analyses differentiate the compensatory roles of two COX isoforms during systemic inflammation in mice ,","year":2017,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute","keywords":"Gene isoform; Inflammation; Cyclooxygenase; Biology; Prostaglandin; Systemic inflammation; Cell biology; Gene; Cancer research; Immunology; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001379217,0.0003442224,0.0001842156,0.0006645775,0.0001661536,0.0003082199,0.0001225619,0.0002615045,0.001742357],"category_scores_gemma":[0.0001155861,0.0001928489,0.0003351814,0.0002710996,0.0002988367,0.0002001111,0.0002010172,0.0005786576,0.0003547879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001886076,"about_ca_system_score_gemma":0.0001671627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003314116,"about_ca_topic_score_gemma":0.001076108,"domain_scores_codex":[0.9998609,0.00001126122,0.00001121137,0.00005081667,0.00003289787,0.00003289399],"domain_scores_gemma":[0.9998449,0.00001455893,0.0000660479,0.00001784112,0.0000163027,0.00004025942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001685172,0.00001147234,0.0008024029,0.00001941049,0.000007491788,0.00003726194,0.00001171553,0.00002353724,0.9979578,0.00007361433,0.00001979265,0.0008668856],"study_design_scores_gemma":[0.0000268529,0.0003440525,0.05491741,0.00001395014,0.00009521017,0.0005767785,0.0001169229,0.0006851279,0.9395112,0.0002254212,0.003473946,0.00001318622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866208,0.0005423077,0.007206574,0.0001116626,0.00003814801,0.00003726812,0.00436938,0.0001021664,0.0009717641],"genre_scores_gemma":[0.9798662,0.0008471523,0.008450893,0.000134098,0.00001718737,0.0001155567,0.004837666,0.0001171186,0.005614231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001742357,"threshold_uncertainty_score":0.005828798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06654813143036674,"score_gpt":0.3985346394155434,"score_spread":0.3319865079851766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}