{"id":"W2770532636","doi":"10.1021/acs.biochem.7b00833","title":"Using Tryptophan Mutants To Probe the Structural and Functional Status of <i>Bs</i>SCO, a Copper Binding, Cytochrome <i>c</i> Oxidase Assembly Protein from <i>Bacillus subtilis</i>","year":2017,"lang":"en","type":"article","venue":"Biochemistry","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Cytochrome c oxidase; Oxidase test; Chemistry; Tryptophan; Mutant; Alanine; Cytochrome; Cytochrome c; Bacillus subtilis; Stereochemistry; Biochemistry; Electron Transport Complex IV; Enzyme; Biology; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001332955,0.0003228468,0.0001513868,0.00008033484,0.0001373844,0.0001636876,0.0001974047,0.000247347,0.000496079],"category_scores_gemma":[0.000187533,0.0001052566,0.000213579,0.0001269181,0.0002510245,0.0001176283,0.0001749659,0.0004586846,0.0001378757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003524233,"about_ca_system_score_gemma":0.0001628005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001633493,"about_ca_topic_score_gemma":0.001276934,"domain_scores_codex":[0.999911,0.00001607806,0.000009954991,0.00002015179,0.00002632644,0.00001640498],"domain_scores_gemma":[0.9998142,0.0000357223,0.00007934934,0.00001361406,0.00001871951,0.00003836743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000668779,0.00001598264,0.0001754191,0.00001454011,0.000003707989,0.0000218761,0.00001231794,0.00006386958,0.9993624,0.0000244858,0.00001154392,0.0002270592],"study_design_scores_gemma":[0.0000119164,0.0001403245,0.004025756,0.000003821664,0.000009308496,0.0001270622,0.00002417053,0.001210661,0.9939724,0.00001922888,0.0004494321,0.000005863174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981192,0.0001073817,0.001324713,0.00003475268,0.000007512332,0.00001177344,0.0001120504,0.00002602701,0.0002566238],"genre_scores_gemma":[0.9971263,0.000115857,0.002008042,0.00003441512,0.000003069352,0.00001768849,0.0002583262,0.00002699937,0.0004094092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001633493,"threshold_uncertainty_score":0.003247917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02176741158827247,"score_gpt":0.2696072705886647,"score_spread":0.2478398590003923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}