{"id":"W2770549402","doi":"10.1002/jctb.5521","title":"Protective effects of <i>Lactococcus lactis</i> expressing alcohol dehydrogenase and acetaldehyde dehydrogenase on acute alcoholic liver injury in mice","year":2017,"lang":"en","type":"article","venue":"Journal of Chemical Technology & Biotechnology","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Aldehyde dehydrogenase; Acetaldehyde; Alcohol dehydrogenase; Ethanol; Liver injury; Lactococcus lactis; Ethanol metabolism; Chemistry; Biochemistry; Pharmacology; Alcohol; Endocrinology; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0004474503,0.0004070936,0.00131718,0.001445752,0.0001566772,0.00002128937,0.0006256851,0.001948053,0.000009316987],"category_scores_gemma":[0.001946924,0.0003490449,0.0002126672,0.0003958954,0.00169862,0.000206525,0.0003765711,0.002560554,0.00001241772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002400307,"about_ca_system_score_gemma":0.000206761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001940278,"about_ca_topic_score_gemma":0.000004049497,"domain_scores_codex":[0.9975375,0.00008380121,0.000917577,0.0005145704,0.0003183523,0.0006282277],"domain_scores_gemma":[0.997026,0.0002162315,0.001450067,0.000861361,0.0002004238,0.0002458866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001522832,0.0004756218,0.002324622,0.0003783356,0.0002626735,0.001469972,0.00006183069,2.470443e-7,0.962806,0.0004278414,0.00008628538,0.03018371],"study_design_scores_gemma":[0.005572905,0.001792453,0.001734064,0.001277848,0.0002763351,0.002145346,0.00002511624,0.00006717646,0.9849948,0.00133097,0.0005333496,0.0002496496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890872,0.001475239,0.0001053995,0.007745032,0.0001667589,0.001233619,0.000007546988,0.0001252235,0.00005397803],"genre_scores_gemma":[0.9966859,0.001001442,0.001581258,0.0005263232,0.00007397863,0.00007448572,0.000001375196,0.00004685731,0.000008396627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02993406,"threshold_uncertainty_score":0.9998962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02844812048254036,"score_gpt":0.3472430141889263,"score_spread":0.3187948937063859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}