{"id":"W2770609983","doi":"10.1016/j.biopsych.2017.11.015","title":"The Candidate Schizophrenia Risk Gene DGCR2 Regulates Early Steps of Corticogenesis","year":2017,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; Université de Genève; Institute of Genetics and Genomics of Geneva; Hôpitaux Universitaires de Genève; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Haploinsufficiency; Reelin; Corticogenesis; Missense mutation; Biology; Genetics; Mutation; Neuroscience; Gene; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.000254839,0.0002333332,0.0002731121,0.00003479965,0.001606773,0.0001546894,0.001156071,0.0001288724,0.00002999761],"category_scores_gemma":[0.001059732,0.0001324193,0.0001945751,0.00009266097,0.0005629839,0.00007895701,0.0003057836,0.0001942332,0.00006956901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006987195,"about_ca_system_score_gemma":0.00004647945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005048566,"about_ca_topic_score_gemma":0.00004319998,"domain_scores_codex":[0.9979801,0.0003222706,0.0004153262,0.0006006274,0.0002624407,0.0004192856],"domain_scores_gemma":[0.9977284,0.0004241899,0.0006234208,0.001048879,0.00003264314,0.0001424779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000502845,0.000132229,0.06804942,0.000005805925,0.0000139643,0.00000631051,0.000006740501,0.000004558015,0.9186198,0.00928422,0.0001478139,0.003226269],"study_design_scores_gemma":[0.0004084437,0.0004089803,0.4149917,0.000008382561,0.00002346325,0.00001147308,0.00000320635,0.00005087589,0.5796694,0.003742107,0.0005254701,0.000156504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965166,0.0002167489,0.00007558663,0.0003739958,0.00218448,0.0002433941,0.00009944462,0.00006883544,0.000220843],"genre_scores_gemma":[0.9980462,0.001088833,0.0003287819,0.0001766809,0.0002178037,0.00001595077,7.753328e-7,0.00002136845,0.0001036652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3469423,"threshold_uncertainty_score":0.999693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03802197247512036,"score_gpt":0.2666375800404878,"score_spread":0.2286156075653674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}