{"id":"W2770609983","doi":"10.1016/j.biopsych.2017.11.015","title":"The Candidate Schizophrenia Risk Gene DGCR2 Regulates Early Steps of Corticogenesis","year":2017,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; Université de Genève; Institute of Genetics and Genomics of Geneva; Hôpitaux Universitaires de Genève; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Haploinsufficiency; Reelin; Corticogenesis; Missense mutation; Biology; Genetics; Mutation; Neuroscience; Gene; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001047938,0.0004951662,0.0002695367,0.0004178576,0.0002294702,0.0004231968,0.0002660519,0.0002547578,0.001340208],"category_scores_gemma":[0.0002639498,0.0001944802,0.0002612018,0.0001451352,0.0002303367,0.0001231125,0.0003375685,0.0004119066,0.0002468588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004593889,"about_ca_system_score_gemma":0.0004521167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0048757,"about_ca_topic_score_gemma":0.008618705,"domain_scores_codex":[0.9998692,0.00001278861,0.000004700106,0.00004441913,0.00003001776,0.00003892048],"domain_scores_gemma":[0.9998466,0.00001866644,0.00005678895,0.00001251693,0.00001940971,0.00004599738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003682846,0.00001544551,0.009379896,0.0000423516,0.0000295273,0.0005990288,0.00004197668,0.0001987026,0.9840474,0.0005368508,0.0002449404,0.004495687],"study_design_scores_gemma":[0.00009706917,0.0002287702,0.396772,0.00005955938,0.000155769,0.002892755,0.0002891022,0.002608424,0.5875916,0.001082562,0.008168057,0.00005427771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908316,0.001982715,0.003207498,0.0002006136,0.00005222649,0.00001346122,0.00121242,0.0001386683,0.002360833],"genre_scores_gemma":[0.9943725,0.0005896444,0.001560542,0.00007396118,0.000008207734,0.000009441083,0.0008351965,0.00005752686,0.002493011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0048757,"threshold_uncertainty_score":0.009694636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03802197247512036,"score_gpt":0.2666375800404878,"score_spread":0.2286156075653674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}