{"id":"W2770650858","doi":"","title":"Functional analysis of a novel RING-type ubiquitin ligase which controls LUBAC activity","year":2017,"lang":"en","type":"article","venue":"The Japanese Biochemical Society/The Molecular Biology Society of Japan","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Programs for Assessment of Technology in Health Research Institute","funders":"","keywords":"Ubiquitin ligase; Ubiquitin-Protein Ligases; Ubiquitin; DNA ligase; Chemistry; Cell biology; Biology; Biochemistry; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00124024,0.0004077281,0.0006921878,0.00002492115,0.0006327055,0.00004324518,0.001354208,0.0007396392,0.00004319133],"category_scores_gemma":[0.0004927958,0.0002790488,0.001723856,0.0004088168,0.002058894,0.000009533765,0.0007690621,0.0004589983,0.000003093454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003500221,"about_ca_system_score_gemma":0.0001656581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002752531,"about_ca_topic_score_gemma":0.00001792778,"domain_scores_codex":[0.9977661,0.0001891245,0.0004893154,0.0006773816,0.0003255022,0.0005526245],"domain_scores_gemma":[0.9967024,0.0001634799,0.0007683855,0.001732476,0.0004974533,0.0001357475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002266958,0.0002492711,0.001880261,0.00003809071,0.004015008,9.664913e-8,0.0005955537,0.00007571671,0.9908255,0.0002664641,0.001610722,0.0002165682],"study_design_scores_gemma":[0.001360314,0.0002986811,0.006387903,0.00002101727,0.001045501,0.00000780979,0.0006139372,0.001999586,0.9868057,0.00009363813,0.001012856,0.0003530844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932142,0.001145991,0.001583307,0.002964649,0.0001391498,0.0004664265,0.0001949251,0.00002049333,0.0002707895],"genre_scores_gemma":[0.9972113,0.0002361342,0.0007861952,0.000953597,0.0002398485,0.00005861976,0.000278622,0.00003602237,0.0001996074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004507642,"threshold_uncertainty_score":0.9999661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02408058771406785,"score_gpt":0.2889920141477252,"score_spread":0.2649114264336574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}