{"id":"W2770650858","doi":"","title":"Functional analysis of a novel RING-type ubiquitin ligase which controls LUBAC activity","year":2017,"lang":"en","type":"article","venue":"The Japanese Biochemical Society/The Molecular Biology Society of Japan","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Programs for Assessment of Technology in Health Research Institute","funders":"","keywords":"Ubiquitin ligase; Ubiquitin-Protein Ligases; Ubiquitin; DNA ligase; Chemistry; Cell biology; Biology; Biochemistry; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001854528,0.0004669424,0.0003558333,0.0003819118,0.0003915372,0.0003979734,0.000385983,0.0003159498,0.001280819],"category_scores_gemma":[0.000170565,0.0001645754,0.0003927595,0.0002263085,0.0002891512,0.0003010583,0.0001981527,0.0004215216,0.0005909914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006654873,"about_ca_system_score_gemma":0.0004142233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001191886,"about_ca_topic_score_gemma":0.0007896918,"domain_scores_codex":[0.9998953,0.00001228307,0.00001286406,0.00003072435,0.00001963014,0.00002904773],"domain_scores_gemma":[0.9998622,0.00001966098,0.00002944027,0.00001581444,0.00001884801,0.00005405901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001553853,0.00002771645,0.0003145408,0.00002539478,0.000007524702,0.0001255262,0.000008138175,0.00005113133,0.9985421,0.0001610157,0.00003318256,0.0005484292],"study_design_scores_gemma":[0.00002952453,0.00007487254,0.003360338,0.00000214945,0.00003521146,0.0005532274,0.00002793274,0.001735697,0.9917952,0.00006962654,0.002308275,0.000007957658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935521,0.001133464,0.003820189,0.0001229559,0.00004038118,0.00002871664,0.0006115176,0.00007390932,0.0006168104],"genre_scores_gemma":[0.9915446,0.0004175159,0.003748279,0.00004327822,0.00001421936,0.00002132602,0.001873302,0.000030003,0.002307573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001280819,"threshold_uncertainty_score":0.004828453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02408058771406785,"score_gpt":0.2889920141477252,"score_spread":0.2649114264336574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}