{"id":"W2770790219","doi":"10.1182/bloodadvances.2017011601","title":"CD86 regulates myeloma cell survival","year":2017,"lang":"en","type":"article","venue":"Blood Advances","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Cancer Institute","keywords":"Multiple myeloma; Cancer research; Downregulation and upregulation; Gene silencing; CD86; Signal transduction; CD28; Biology; Medicine; Cell biology; T cell; Immunology; Genetics; Gene; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006451581,0.0001225763,0.0001425022,0.0001655462,0.0002733821,0.0004599978,0.00008139924,0.0001857523,0.001377599],"category_scores_gemma":[0.0001061243,0.00005738912,0.0001021713,0.0001657454,0.0001401676,0.0001385073,0.0002619494,0.0004547185,0.0005486239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002669384,"about_ca_system_score_gemma":0.0001964286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003485524,"about_ca_topic_score_gemma":0.0005261209,"domain_scores_codex":[0.9998785,0.00001892734,0.000005873916,0.00001950026,0.00003033376,0.00004695932],"domain_scores_gemma":[0.9999335,0.000005990297,0.00002212333,0.00000484649,0.00001439368,0.00001902424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003791954,0.00008726382,0.004719053,0.00006850102,0.00001262235,0.0001108537,0.00006077095,0.0001962537,0.9749544,0.000791104,0.0008381066,0.01778183],"study_design_scores_gemma":[0.00007670255,0.0006429788,0.1429501,0.00004068905,0.00008508776,0.001173651,0.0003848801,0.003802362,0.8041703,0.001156979,0.0454975,0.00001883129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841485,0.007999166,0.001708938,0.0003970608,0.0000527807,0.00001316613,0.0003013726,0.0001074743,0.005271614],"genre_scores_gemma":[0.9949868,0.001721535,0.0003869943,0.00007469652,0.00001835894,0.000007747584,0.0002107222,0.000008559984,0.002584707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001377599,"threshold_uncertainty_score":0.004608572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02555613416927207,"score_gpt":0.3246470050546573,"score_spread":0.2990908708853853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}