{"id":"W2770873389","doi":"10.1007/s00535-017-1417-z","title":"Efficacy and safety of twice-daily rabeprazole maintenance therapy for patients with reflux esophagitis refractory to standard once-daily proton pump inhibitor: the Japan-based EXTEND study","year":2017,"lang":"en","type":"article","venue":"Journal of Gastroenterology","topic":"Gastroesophageal reflux and treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eisai Canada; Eisai; EA Pharma Co., Ltd.","keywords":"Rabeprazole; Refractory (planetary science); Reflux esophagitis; Medicine; Proton-pump inhibitor; Hepatology; Esophagitis; Abdominal surgery; Colorectal surgery; Reflux; Surgical oncology; Internal medicine; Gastroenterology; Maintenance therapy; Chemotherapy; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006602849,0.0002999387,0.0008682463,0.0001577714,0.0002706057,0.00004719728,0.0003364971,0.00007275093,0.00001545506],"category_scores_gemma":[0.0002779693,0.0001657052,0.000150935,0.0000475254,0.000299906,0.0001796409,0.00006547118,0.0003465102,0.000001279749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001356154,"about_ca_system_score_gemma":0.0001358079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009421158,"about_ca_topic_score_gemma":0.00001814984,"domain_scores_codex":[0.9977488,0.0001641363,0.0007542381,0.0003234056,0.0005461788,0.0004632297],"domain_scores_gemma":[0.996961,0.0001388151,0.001239971,0.0006274363,0.0007643181,0.000268484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1009526,0.002229924,0.887755,0.00003990385,0.0005028529,0.0001278869,0.0003777774,0.00001021903,0.0002610498,0.000001206019,0.0001758539,0.007565659],"study_design_scores_gemma":[0.05289298,0.110448,0.8350415,0.0002095318,0.000205442,0.00004815434,0.00009574778,0.000003955365,0.0005664526,0.000007471565,0.0004339521,0.0000468898],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947774,0.00005601643,0.0003090559,0.001146061,0.0002055989,0.003401904,0.00007121602,0.000008314823,0.00002437664],"genre_scores_gemma":[0.9977953,0.00003346581,0.001267219,0.0005686205,0.0001336961,0.0001019942,0.000006963713,0.0000416212,0.00005105491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1082181,"threshold_uncertainty_score":0.6757263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01349148123515237,"score_gpt":0.2938889032018865,"score_spread":0.2803974219667341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}