{"id":"W2770965419","doi":"10.1021/acs.biochem.7b01017","title":"Genetically Encoded Chemical Decaging in Living Bacteria","year":2017,"lang":"en","type":"article","venue":"Biochemistry","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Science and Technology of the People's Republic of China; Institute of Genetics; National Natural Science Foundation of China","keywords":"Escherichia coli; Bacteria; Indole test; Enzyme; Biochemistry; Microorganism; Chemistry; Intracellular; Function (biology); Biology; Microbiology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001027556,0.0002199364,0.0002039821,0.00001176461,0.0002229595,0.0001767581,0.0008718322,0.0002722081,0.001436959],"category_scores_gemma":[0.0005166943,0.0002529198,0.00009095213,0.00003945529,0.0001919197,0.00006800618,0.0003465742,0.0003020126,0.00004038755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009673592,"about_ca_system_score_gemma":0.00008088347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002544674,"about_ca_topic_score_gemma":0.000003560587,"domain_scores_codex":[0.9986154,0.000003530094,0.0003168379,0.0005188388,0.0001600203,0.0003853541],"domain_scores_gemma":[0.9982556,0.00009582695,0.0001591912,0.001275723,0.00003755529,0.0001761373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008080086,0.00009978111,0.014398,0.0001140743,0.00001181673,0.00001229976,0.00003064525,5.055171e-7,0.9833268,0.00002861782,0.0002024815,0.001766886],"study_design_scores_gemma":[0.000262316,9.475264e-7,0.001560127,0.0002007115,0.00001294128,0.00002570893,0.00005216596,0.000214978,0.9959853,0.0001119865,0.001279652,0.0002931641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9380125,0.00007075759,0.00002201199,0.0002753431,0.00002629192,0.00002906338,0.0000223951,0.00007703807,0.06146456],"genre_scores_gemma":[0.996184,0.00003536039,0.001164657,0.00002962846,0.000401214,0.00005625609,0.00003996237,0.00002728494,0.002061618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05940294,"threshold_uncertainty_score":0.9999923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0150496380286458,"score_gpt":0.2718212561812489,"score_spread":0.2567716181526031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}