{"id":"W2771134803","doi":"10.1016/j.ccell.2017.11.017","title":"Glut3 Addiction: A Druggable Vulnerability in Glioblastoma","year":2017,"lang":"en","type":"letter","venue":"Cancer Cell","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Druggability; GLUT3; Context (archaeology); Blockade; Addiction; Biology; Vulnerability (computing); Cancer research; Neuroscience; Genetics; Gene; Receptor; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001024621,0.000352842,0.0006634754,0.000108538,0.0001105211,0.00005012074,0.0001815962,0.0005995292,0.003485681],"category_scores_gemma":[0.00002009224,0.000299601,0.0002237968,0.00008950457,0.00009004007,0.00008119408,0.00005721396,0.001009212,0.0002041722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001103099,"about_ca_system_score_gemma":0.0003338204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003169224,"about_ca_topic_score_gemma":0.001089151,"domain_scores_codex":[0.9982187,0.00004994943,0.0003013396,0.0006486321,0.0003297016,0.0004516337],"domain_scores_gemma":[0.9984754,0.0000670352,0.0002026434,0.00105585,0.00009332752,0.0001057954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000691215,0.0002236155,0.005516062,0.000305474,0.00008174933,0.002622698,0.0000628723,0.000006804566,0.00005001549,6.709702e-7,0.9882169,0.002843967],"study_design_scores_gemma":[0.002368752,0.0002116792,0.002828267,0.0005269698,0.0002758744,0.00003325982,0.000008925698,0.00002896992,0.003721985,0.00002390532,0.9897218,0.0002496268],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.07735215,0.03541139,0.000002725054,0.7919514,0.003766124,0.002313301,0.0005679391,0.0001964025,0.08843863],"genre_scores_gemma":[0.2687651,0.004280664,0.0002152854,0.6536643,0.01807358,0.004259876,0.0006442383,0.0003074984,0.04978947],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1914129,"threshold_uncertainty_score":0.9999456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01946871872644187,"score_gpt":0.2885369334274299,"score_spread":0.2690682147009881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}