{"id":"W2771414232","doi":"10.1002/cncr.31138","title":"Dose, schedule, safety, and efficacy of guadecitabine in relapsed or refractory acute myeloid leukemia","year":2017,"lang":"en","type":"article","venue":"Cancer","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Stand Up To Cancer; Astex Pharmaceuticals","keywords":"Medicine; Regimen; Internal medicine; Adverse effect; Gastroenterology; Refractory (planetary science); Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009715021,0.0002470248,0.0005667744,0.000219289,0.0001814435,0.0002892317,0.000302743,0.0003115557,0.000860566],"category_scores_gemma":[0.0009985542,0.000177397,0.0002699845,0.000211593,0.0004341272,0.0002727984,0.0001657272,0.0006720232,0.0001727428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004648086,"about_ca_system_score_gemma":0.000482243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003660589,"about_ca_topic_score_gemma":0.001063039,"domain_scores_codex":[0.9996698,0.0001853528,0.00002826213,0.00003836497,0.00004063649,0.00003756638],"domain_scores_gemma":[0.9995582,0.0001178075,0.0001550764,0.00005633651,0.00001407369,0.00009858535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3751516,0.02424837,0.04431665,0.0005693898,0.000624585,0.0003746572,0.0003122867,0.006981418,0.1932639,0.0004995273,0.002595209,0.3510625],"study_design_scores_gemma":[0.1388107,0.6533784,0.1260087,0.00009112436,0.0008118326,0.001579368,0.0001328103,0.006115788,0.0643262,0.001032775,0.007654467,0.00005779625],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985757,0.0007847262,0.0001367871,0.00005747367,0.00001165383,0.0001060596,0.00006922262,0.00001247344,0.0002457593],"genre_scores_gemma":[0.9988137,0.0004078909,0.0003445215,0.00006537099,0.00002385042,0.00009170262,0.0001068181,0.000004567521,0.0001415188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009715021,"threshold_uncertainty_score":0.005137801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03316210548809689,"score_gpt":0.3550695895597498,"score_spread":0.3219074840716529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}