{"id":"W2771455181","doi":"10.1152/ajpendo.00293.2017","title":"Increased body fat mass explains the positive association between circulating estradiol and insulin resistance in postmenopausal women","year":2017,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Theratechnologies (Canada); Université de Sherbrooke; Université Laval","funders":"Core Research for Evolutional Science and Technology; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; Government of Canada; Diabète Québec; Canadian Diabetes Association","keywords":"Internal medicine; Endocrinology; Insulin resistance; Estrone; Adiponectin; Estrogen; Medicine; Insulin; Adipose tissue; Triglyceride; Population; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003623888,0.0001711226,0.0004614475,0.00007144832,0.000312686,0.00002692047,0.000236386,0.0001235882,0.00000139575],"category_scores_gemma":[0.000327715,0.0001245007,0.00005510792,0.00005142218,0.0005485213,0.00002202767,0.00009392745,0.0004662352,6.586183e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003093822,"about_ca_system_score_gemma":0.00005502336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005455067,"about_ca_topic_score_gemma":0.000005469988,"domain_scores_codex":[0.9984971,0.0004866222,0.0003056854,0.0002375939,0.00008508505,0.0003879102],"domain_scores_gemma":[0.9986495,0.0001516119,0.0007947051,0.0002229615,0.00007986381,0.0001013413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004170712,0.00003625128,0.03754085,0.000006640564,0.0005337588,0.00003187309,0.0004182282,0.00000471213,0.9546363,0.0004327217,0.00002798874,0.005913559],"study_design_scores_gemma":[0.001515151,0.0005837812,0.9776373,0.00002028329,0.0001050566,0.00008612459,0.0004979153,0.000004387966,0.017822,0.0009700642,0.0006052446,0.0001527237],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950199,0.003986978,0.00001992651,0.0005817551,0.0001163516,0.0001124029,0.00001616554,0.000003348108,0.0001431539],"genre_scores_gemma":[0.9964278,0.00268681,0.000295322,0.0001878029,0.0003532814,0.000009179342,0.000008301647,0.00001246313,0.00001908689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9400964,"threshold_uncertainty_score":0.5076991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004731693219224405,"score_gpt":0.236518360012398,"score_spread":0.2317866667931736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}