{"id":"W2771661958","doi":"10.1093/carcin/bgx134","title":"MicroRNA-128-3p-mediated depletion of Drosha promotes lung cancer cell migration","year":2017,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Cancer Centre","funders":"Aboca S.p.A. Società Agricola; Associazione Italiana per la Ricerca sul Cancro; ArcelorMittal","keywords":"Drosha; Dicer; microRNA; Biology; Downregulation and upregulation; Cancer research; Lung cancer; Cancer; Epithelial–mesenchymal transition; Phenotype; Ribonuclease III; Metastasis; RNA interference; Transfection; Pathology; Cell culture; Small interfering RNA; Genetics; Medicine; Gene; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009824752,0.000146175,0.0001433841,0.00002933846,0.0001631222,0.00003064888,0.0002404017,0.000160091,0.00005593137],"category_scores_gemma":[0.00008052871,0.0001496821,0.0001119647,0.00003337338,0.00008463389,0.00001100946,0.00008805296,0.00002764491,0.000004272115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004391197,"about_ca_system_score_gemma":0.000108967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005206225,"about_ca_topic_score_gemma":0.0005256926,"domain_scores_codex":[0.9991344,0.00004225157,0.0002137259,0.0003084764,0.0001234887,0.0001776339],"domain_scores_gemma":[0.9988011,0.000006691906,0.0003016888,0.0006155006,0.0002026298,0.00007235296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003631611,0.00003706227,0.2029378,0.00008869451,0.00003055491,7.197351e-7,0.00003339867,0.0000186129,0.7954901,0.00000250807,0.0009165949,0.0004076539],"study_design_scores_gemma":[0.0003012295,0.00002868171,0.2857942,0.00002037136,0.00005127243,0.000001208427,0.00001044923,0.0002903006,0.7126174,0.00000371387,0.0007609726,0.0001202178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931175,0.005658382,0.0003382671,0.0001229129,0.0001503137,0.0002873119,0.0001284327,0.00001125827,0.0001856599],"genre_scores_gemma":[0.9984136,0.0004930496,0.0002196453,0.00003280922,0.0001945892,0.00005118237,0.0003639788,0.00002880363,0.0002023361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0828727,"threshold_uncertainty_score":0.610386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01050959280417105,"score_gpt":0.2579540075771686,"score_spread":0.2474444147729976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}