{"id":"W2771769397","doi":"10.1002/cbic.201700660","title":"<i>O</i><sup>4</sup>‐Alkylated‐2‐Deoxyuridine Repair by <i>O</i><sup>6</sup>‐Alkylguanine DNA Alkyltransferase is Augmented by a C5‐Fluorine Modification","year":2017,"lang":"en","type":"article","venue":"ChemBioChem","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Concordia University; Compute Canada","keywords":"Chemistry; Deoxyuridine; Alkylation; Adduct; Stereochemistry; Thymine; Uracil; DNA; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009394027,0.0002464125,0.0001718691,0.00007297491,0.00007836051,0.0002201899,0.0002139853,0.0001965867,0.0009210131],"category_scores_gemma":[0.0002400361,0.0001426039,0.0002105096,0.00008783774,0.0001402935,0.0001398277,0.0001267595,0.0002001308,0.0002880325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001909673,"about_ca_system_score_gemma":0.0001407078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007301269,"about_ca_topic_score_gemma":0.0007098514,"domain_scores_codex":[0.9999233,0.00001312437,0.000006012873,0.00001485654,0.00002735281,0.00001546612],"domain_scores_gemma":[0.9998814,0.00002041321,0.00005855317,0.00001097818,0.00001526583,0.0000134049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001225883,0.00001350455,0.0005334573,0.00005136036,0.00001349443,0.00004227481,0.0000120928,0.001178221,0.9962632,0.0001267279,0.00002778622,0.00161516],"study_design_scores_gemma":[0.000008454617,0.000318731,0.00209779,0.000004503782,0.00002062845,0.0001005979,0.00001307947,0.00375285,0.992407,0.00003734602,0.001232258,0.000006827972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964293,0.0002054163,0.002366154,0.00001361203,0.00000883876,0.000007308209,0.00006163318,0.00006208672,0.0008456822],"genre_scores_gemma":[0.9970278,0.0001075314,0.002160079,0.00001054384,0.000002316333,0.000005186952,0.0001429846,0.00001557659,0.0005280207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009210131,"threshold_uncertainty_score":0.003081083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009177875571820635,"score_gpt":0.2402239049138992,"score_spread":0.2310460293420785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}