{"id":"W2771791410","doi":"10.1016/s1473-3099(17)30691-6","title":"Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study","year":2017,"lang":"en","type":"article","venue":"The Lancet Infectious Diseases","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":691,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"School of Medicine, Johns Hopkins University; Centers for Disease Control and Prevention; Grand Challenges Canada; Fogarty International Center; Australian Government; South African Medical Research Council; Newton Fund; PATH; Netherlands Institute of Government; World Health Organization; Clinton Foundation; World Bank Group; Bill and Melinda Gates Foundation; National Institutes of Health; U.S. Department of Health and Human Services; Global Fund to Fight AIDS, Tuberculosis and Malaria; Government of the United Kingdom; Henry M. Jackson Foundation; National Institute of Allergy and Infectious Diseases; Medical Research Council; London School of Hygiene and Tropical Medicine; National Department of Health","keywords":"Medicine; Tuberculosis; Sputum; Rifampicin; Mycobacterium tuberculosis; Drug resistance; Internal medicine; Human immunodeficiency virus (HIV); Virology; Pathology; Microbiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01169136,0.001090749,0.0007269277,0.001674791,0.0007470634,0.001290706,0.001039375,0.001423349,0.0007423575],"category_scores_gemma":[0.02504892,0.001234875,0.001240639,0.001228985,0.0009105011,0.001283742,0.001298054,0.0009660973,0.0004448101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006076208,"about_ca_system_score_gemma":0.0005063702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001821448,"about_ca_topic_score_gemma":0.001382079,"domain_scores_codex":[0.9893988,0.005348223,0.001030006,0.001747145,0.001871904,0.0006039387],"domain_scores_gemma":[0.978479,0.006169638,0.007253364,0.002802429,0.003561798,0.001733684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00110007,0.0002934417,0.9965426,0.00002256323,0.0001552862,0.0001022761,0.0002246791,0.000044231,0.0003491151,0.00001041785,0.00004331445,0.001111894],"study_design_scores_gemma":[0.0003131432,0.003605386,0.9932648,0.0000192573,0.0002406987,0.00114289,0.0002149732,0.000675617,0.0003163037,0.0000168088,0.0001675154,0.00002248704],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991931,0.0002261752,0.000295882,0.00001591489,0.000005294296,0.00007194707,0.00007658346,0.000005101876,0.00011012],"genre_scores_gemma":[0.9992035,0.00005853155,0.0004463833,0.00003009575,0.00001173044,0.00005396994,0.0001501566,0.000003722846,0.00004203737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01169136,"threshold_uncertainty_score":0.06183058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02561523390362307,"score_gpt":0.344523561469046,"score_spread":0.3189083275654229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}