{"id":"W2771985191","doi":"10.3390/molecules22122155","title":"De Novo RNA Sequencing and Expression Analysis of Aconitum carmichaelii to Analyze Key Genes Involved in the Biosynthesis of Diterpene Alkaloids","year":2017,"lang":"en","type":"article","venue":"Molecules","topic":"Plant-based Medicinal Research","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Chiba University; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; National University of Singapore; Research Organization of Information and Systems; Japan Agency for Medical Research and Development","keywords":"Transcriptome; Diterpene; Computational biology; Biology; De novo transcriptome assembly; Biosynthesis; Aconitine; Gene; Biochemistry; Gene expression; Pharmacology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002783328,0.0006302471,0.0008615453,0.0008039688,0.0006291155,0.0005407342,0.000347976,0.0004298757,0.0006032116],"category_scores_gemma":[0.0003902138,0.0002352069,0.000684501,0.00129342,0.0002339089,0.0002776,0.0004517673,0.0007972912,0.0006185177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004348632,"about_ca_system_score_gemma":0.0006808187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002251712,"about_ca_topic_score_gemma":0.00365957,"domain_scores_codex":[0.9996802,0.00001828063,0.00001744591,0.0001147714,0.0001079892,0.00006139614],"domain_scores_gemma":[0.9997261,0.00006326738,0.00005063659,0.00002581129,0.0001015202,0.000032583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007630055,0.00001987991,0.000649012,0.0001242057,0.000009310135,0.00006514593,0.00008592876,0.0002755703,0.9947884,0.0001103151,0.0001274107,0.003668455],"study_design_scores_gemma":[0.0001007761,0.0008179692,0.2105199,0.0001684158,0.0003149635,0.000758376,0.0006367864,0.02547322,0.7094757,0.001126148,0.05050554,0.0001021963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9176496,0.005476228,0.0350191,0.0004358847,0.0002057619,0.000600924,0.03332087,0.0008034835,0.006488187],"genre_scores_gemma":[0.8258342,0.004493051,0.08478602,0.0009730674,0.0001740988,0.001292768,0.07368069,0.0006124492,0.00815374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002251712,"threshold_uncertainty_score":0.004477143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.117981809176299,"score_gpt":0.4386894587456155,"score_spread":0.3207076495693165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}