{"id":"W2772224228","doi":"10.1101/226894","title":"Transcriptome-wide interrogation of the functional intronome by spliceosome profiling","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"British Columbia Centre on Substance Use","funders":"Division of Biological Infrastructure; Howard Hughes Medical Institute; National Institutes of Health; National Science Foundation","keywords":"Spliceosome; RNA splicing; Intron; Ribosome profiling; RNA; Minor spliceosome; Profiling (computer programming); Transcriptome; splice; Precursor mRNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003110215,0.0002351724,0.0003531319,0.0004562048,0.0002144493,0.0005852489,0.0002079586,0.0002598141,0.0009380133],"category_scores_gemma":[0.0002246176,0.0001638627,0.0002919009,0.0004398683,0.0002670911,0.0003003247,0.0003381549,0.0005871752,0.000670055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002172341,"about_ca_system_score_gemma":0.0001853933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004003383,"about_ca_topic_score_gemma":0.0007141553,"domain_scores_codex":[0.9998596,0.00001467069,0.000006222016,0.00005803283,0.00004244193,0.00001912309],"domain_scores_gemma":[0.9998522,0.00004646321,0.0000287339,0.00002213796,0.00002714976,0.0000233519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005765271,0.00000755781,0.002134321,0.00004625748,0.0000141926,0.00003446141,0.0000346798,0.0003709004,0.9928699,0.0003297241,0.0001941517,0.003906219],"study_design_scores_gemma":[0.00002054025,0.0001066794,0.05061435,0.00002614959,0.00006500889,0.0003159643,0.0001605411,0.01535035,0.9163459,0.002599397,0.01436206,0.00003302404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8957444,0.001657912,0.08666405,0.0002652391,0.00006626394,0.00005509723,0.01121155,0.0009173462,0.003418076],"genre_scores_gemma":[0.9312026,0.001273984,0.05322876,0.0002294754,0.00003675922,0.00009720565,0.01138063,0.0002791824,0.0022715],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009380133,"threshold_uncertainty_score":0.003138006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01354075807883223,"score_gpt":0.2312820550153056,"score_spread":0.2177412969364733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}