{"id":"W2772475936","doi":"10.1111/pcmr.12678","title":"Seeing the light to change colour: An evolutionary perspective on the role of melanopsin in neuroendocrine circuits regulating light‐mediated skin pigmentation","year":2017,"lang":"en","type":"review","venue":"Pigment Cell & Melanoma Research","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Melanopsin; Photopigment; Biology; Melatonin; Pineal gland; Opsin; Neuroscience; Melanosome; Circadian rhythm; Intrinsically photosensitive retinal ganglion cells; Melanin; Retina; Genetics; Retinal; Rhodopsin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003249782,0.0005456622,0.0006446387,0.001539157,0.0002740808,0.0008339304,0.0005154663,0.0008626838,0.002238655],"category_scores_gemma":[0.0003516957,0.0001757206,0.000272855,0.001412655,0.0005887409,0.001454269,0.0006030699,0.001480871,0.0009523265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005235591,"about_ca_system_score_gemma":0.0009699982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009739927,"about_ca_topic_score_gemma":0.001591803,"domain_scores_codex":[0.9999273,0.00001089758,0.00001113352,0.00001823329,0.00002342304,0.000009059388],"domain_scores_gemma":[0.999851,0.00006711041,0.00001866406,0.000004889099,0.00004012995,0.00001805739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005983508,0.00004466353,0.0003549439,0.01474716,0.00007915679,0.0003465845,0.0002372052,0.000457526,0.004515988,0.01190162,0.02081505,0.9464402],"study_design_scores_gemma":[0.000007038799,0.00007072332,0.001683688,0.002802019,0.00006229947,0.001390969,0.0001594659,0.00008846192,0.0005684741,0.004926717,0.9882205,0.00001971191],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001871615,0.9977626,0.0001757854,0.0004056456,0.0002341771,0.000001944043,0.00001079552,0.000006061678,0.001215916],"genre_scores_gemma":[0.0007958438,0.9983728,0.0001333307,0.0001398606,0.0001400909,0.000002586651,0.00001238152,0.000001052659,0.000402011],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002238655,"threshold_uncertainty_score":0.007489085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1754638329889127,"score_gpt":0.4062649572935005,"score_spread":0.2308011243045877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}