{"id":"W2772577952","doi":"10.1002/prca.201700120","title":"Detection of the Human Anti‐ActRII Antibody Bimagrumab in Serum by Means of Affinity Purification, Tryptic Digestion, and LC‐HRMS","year":2017,"lang":"en","type":"article","venue":"PROTEOMICS - CLINICAL APPLICATIONS","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Ammonium sulfate precipitation; Antibody; Chromatography; Chemistry; Computational biology; Medicine; Biochemistry; Biology; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001293835,0.001013053,0.0004265842,0.001414037,0.0004487036,0.000531144,0.0004753672,0.0009053029,0.001254464],"category_scores_gemma":[0.001261487,0.0003124484,0.0003848895,0.0004147817,0.0005485321,0.0003118562,0.0005236294,0.0007001434,0.00118438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004209673,"about_ca_system_score_gemma":0.0009315645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006071942,"about_ca_topic_score_gemma":0.001182983,"domain_scores_codex":[0.9985115,0.0002859434,0.00008404716,0.0003248378,0.0006723494,0.0001213316],"domain_scores_gemma":[0.9995757,0.0001232944,0.00009766037,0.00003833136,0.0001069583,0.00005794187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001626675,0.0000860958,0.001955833,0.0001230425,0.00003315856,0.00008315615,0.00003324725,0.00009695855,0.9869013,0.0001376907,0.000170258,0.01021653],"study_design_scores_gemma":[0.0000278433,0.0004441543,0.007789987,0.00003298766,0.00004805062,0.001327435,0.00003701433,0.004965953,0.9823254,0.000149117,0.002831032,0.00002105235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7495155,0.01099941,0.2281234,0.0009674686,0.0003639783,0.0006939431,0.001259704,0.001681014,0.006395584],"genre_scores_gemma":[0.7373097,0.0038053,0.2496601,0.001464527,0.0001407457,0.0005674838,0.001479468,0.0001057145,0.005467131],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001414037,"threshold_uncertainty_score":0.006842554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01885550707296695,"score_gpt":0.340287954591282,"score_spread":0.321432447518315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}