{"id":"W2772940414","doi":"10.1038/s41564-017-0079-1","title":"Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides","year":2017,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Polysaccharides and Plant Cell Walls","field":"Agricultural and Biological Sciences","cited_by":419,"is_retracted":false,"has_abstract":false,"ca_institutions":"Agriculture and Agri-Food Canada; University of Lethbridge","funders":"Biotechnology and Biological Sciences Research Council; European Commission; Newcastle University; Diamond Light Source; Wellcome Trust","keywords":"Bacteroides thetaiotaomicron; Pectin; Polysaccharide; Glycoside hydrolase; Bacteroides; Biochemistry; Glycan; Bacteroides fragilis; Enzyme; Rhamnose; Cell wall; Biology; Bacteria; Glycosyltransferase; Chemistry; Microbiology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001877466,0.0002350688,0.0003742823,0.00002155351,0.0005171224,0.00009179924,0.000747758,0.0007357594,0.0003051597],"category_scores_gemma":[0.00007302776,0.0001006052,0.0001013089,0.00009709291,0.000153771,0.00009898091,0.0001409873,0.0007621007,0.00003484602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005071412,"about_ca_system_score_gemma":0.000009549325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001490474,"about_ca_topic_score_gemma":0.01297988,"domain_scores_codex":[0.9986202,0.0001173529,0.0002391465,0.0004597651,0.00004215883,0.0005214317],"domain_scores_gemma":[0.9993829,0.0001539468,0.0001888979,0.0001520976,0.00003902613,0.00008309073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003959684,0.00007499725,0.02474259,0.000005257511,0.00001688079,0.00004314882,0.00002631623,1.659528e-7,0.9645916,0.00004056118,0.009288655,0.001130208],"study_design_scores_gemma":[0.0009128221,0.0006144698,0.5404134,0.0001003996,0.00003220111,0.000160535,0.0001397711,0.00001088158,0.3916087,0.0005928919,0.06465612,0.0007578565],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945605,0.001963658,7.391888e-8,0.001841176,0.0003362678,0.0001988575,0.000734285,0.00005253662,0.0003126198],"genre_scores_gemma":[0.9978557,0.0001072866,0.000007458131,0.0006353579,0.000129318,0.00001013289,0.0007674808,0.000001959584,0.0004853695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5729829,"threshold_uncertainty_score":0.7243078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0169584133174335,"score_gpt":0.2276040741962154,"score_spread":0.2106456608787819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}