{"id":"W2773342423","doi":"10.1016/j.stemcr.2017.11.002","title":"Breast Cancers Activate Stromal Fibroblast-Induced Suppression of Progenitors in Adjacent Normal Tissue","year":2017,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Manitoba; Research Institute in Oncology and Hematology; BC Cancer Agency; CancerCare Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; Research Manitoba","keywords":"Biology; Stromal cell; Progenitor cell; Cancer research; Fibroblast; Epithelium; Cell growth; Breast cancer; Cell biology; Cancer; Cell culture; Stem cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002130839,0.0001891364,0.0004383618,0.00009373119,0.00009581863,0.0000246728,0.000100169,0.0001023987,0.0001741001],"category_scores_gemma":[0.000009256742,0.0001606788,0.0001067503,0.00006972186,0.00005745711,0.0001537011,0.0001089159,0.000181981,0.00000353326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002229603,"about_ca_system_score_gemma":0.0004544712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002712325,"about_ca_topic_score_gemma":0.0002672755,"domain_scores_codex":[0.9983225,0.00002762285,0.0005202693,0.0003791552,0.0004026458,0.0003477399],"domain_scores_gemma":[0.9981869,0.00001202579,0.0006787385,0.0008245105,0.0000923573,0.0002054176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004894972,0.0001665706,0.06133315,0.0005484134,0.00003914214,0.001483028,0.0002996723,0.00003100853,0.8847017,0.000001265559,0.000444171,0.05046239],"study_design_scores_gemma":[0.0009290676,0.000281187,0.04758345,0.0005271155,0.00006225735,0.0006489321,0.0001991711,0.000008992153,0.947279,0.00000194253,0.002334246,0.0001446649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990124,0.0001427289,0.000004746134,0.00008221706,0.0006995135,0.0005832024,0.00001917308,0.00001908442,0.008325338],"genre_scores_gemma":[0.9978122,0.00004236826,0.0001390524,0.000006611927,0.000167808,0.00002935883,0.00001283547,0.00002985549,0.00175993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06257729,"threshold_uncertainty_score":0.655229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0175735440623235,"score_gpt":0.2808690718318515,"score_spread":0.263295527769528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}