{"id":"W2773342423","doi":"10.1016/j.stemcr.2017.11.002","title":"Breast Cancers Activate Stromal Fibroblast-Induced Suppression of Progenitors in Adjacent Normal Tissue","year":2017,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Manitoba; Research Institute in Oncology and Hematology; BC Cancer Agency; CancerCare Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; Research Manitoba","keywords":"Biology; Stromal cell; Progenitor cell; Cancer research; Fibroblast; Epithelium; Cell growth; Breast cancer; Cell biology; Cancer; Cell culture; Stem cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001047714,0.0002364334,0.0001519451,0.0002792391,0.0001150305,0.0002617185,0.00007562053,0.0001116232,0.001370182],"category_scores_gemma":[0.0001038052,0.000104006,0.0001429577,0.0001405498,0.0001331003,0.00009457889,0.0002691382,0.000251389,0.0003900219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008667618,"about_ca_system_score_gemma":0.0001416156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003360421,"about_ca_topic_score_gemma":0.0005381679,"domain_scores_codex":[0.9998769,0.00003154664,0.00000818827,0.00001682988,0.00004301749,0.00002343952],"domain_scores_gemma":[0.9999236,0.00001767311,0.00001493655,0.00001222114,0.000009382744,0.0000222454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000102495,0.00001977192,0.0007635514,0.00002569909,0.000004449589,0.0001455851,0.00003279155,0.00002896061,0.996947,0.0001495604,0.00003711636,0.001743154],"study_design_scores_gemma":[0.00001652387,0.0002983944,0.02089926,0.000008657868,0.00001892765,0.00153223,0.0001524727,0.0009247641,0.9708295,0.0001356217,0.005179732,0.000003760371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995402,0.001083969,0.001201863,0.00003083735,0.00001069298,0.00001956255,0.0001693181,0.00004354004,0.002038285],"genre_scores_gemma":[0.9972354,0.0004797164,0.0006288407,0.00001829791,0.000004181857,0.0000133801,0.000195378,0.000007122226,0.001417769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001370182,"threshold_uncertainty_score":0.004583776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0175735440623235,"score_gpt":0.2808690718318515,"score_spread":0.263295527769528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}