{"id":"W2773559481","doi":"10.1007/978-1-4939-7498-6_23","title":"Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis","year":2017,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Cancer Risks and Factors","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Armand Frappier Museum; Institut National de la Recherche Scientifique; Université du Québec à Montréal","funders":"Canadian Institutes of Health Research","keywords":"Fetus; Estrogen; Endocrine system; Trophoblast; Adrenocortical carcinoma; Placenta; Androgen; Pregnancy; Endocrinology; Internal medicine; Adrenal cortex; Choriocarcinoma; Biology; Hormone; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004241928,0.0002042816,0.0005464273,0.0001850468,0.00009635326,0.00001854484,0.0001851877,0.0001477823,0.00005929133],"category_scores_gemma":[0.0004238596,0.0001627867,0.0001070797,0.00008079416,0.0001787105,0.00002227819,0.0001039598,0.0002794822,0.00000518235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000912909,"about_ca_system_score_gemma":0.00003716326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00085488,"about_ca_topic_score_gemma":0.00006691564,"domain_scores_codex":[0.9984254,0.0004278581,0.0003311238,0.0004589143,0.00009726261,0.0002594573],"domain_scores_gemma":[0.9989043,0.0001411576,0.0001338742,0.0006174814,0.00004406177,0.0001590714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005197821,0.0003344458,0.343452,0.00001305265,0.0000978651,0.000092619,0.000663494,5.270772e-7,0.5974026,0.0001861703,0.00001802487,0.0572194],"study_design_scores_gemma":[0.001330748,0.002138019,0.2614804,0.00003364644,0.0001189256,0.00003217938,0.0006120893,0.00002114954,0.7332984,0.00021514,0.0005721244,0.0001471581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872654,0.0003132481,0.01046539,0.0003348665,0.0002326761,0.000767547,0.00003552295,0.00001150321,0.0005738633],"genre_scores_gemma":[0.9262483,0.00002507262,0.07343735,0.0001336726,0.00005495117,0.00004969431,0.000004956474,0.00001998786,0.00002607726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1358958,"threshold_uncertainty_score":0.6638247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03452317561849114,"score_gpt":0.4402375442280573,"score_spread":0.4057143686095662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}