{"id":"W277399393","doi":"10.1182/blood.v124.21.3064.3064","title":"Efficacy and Safety of Frontline Bortezomib, Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (VR-CAP) Vs R-CHOP in a Subset of Newly Diagnosed Mantle Cell Lymphoma (MCL) Patients (Pts) Medically Eligible for Transplantation in the Randomized Phase 3 LYM-3002 Study (NCT00722137)","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Rituximab; Internal medicine; Clinical endpoint; Transplantation; Prednisone; CHOP; Regimen; Bortezomib; Mantle cell lymphoma; Vincristine; Oncology; Autologous stem-cell transplantation; Gastroenterology; Cyclophosphamide; Adverse effect; Urology; Surgery; Lymphoma; Clinical trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001683352,0.0006034664,0.001038942,0.0002165356,0.0001964593,0.0008183261,0.0005922272,0.0006777783,0.002615329],"category_scores_gemma":[0.0009977848,0.0002918894,0.001183088,0.000259542,0.0004351406,0.0004942639,0.0002582011,0.00177361,0.0003905916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007784494,"about_ca_system_score_gemma":0.0007526313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007384592,"about_ca_topic_score_gemma":0.002728556,"domain_scores_codex":[0.9995055,0.0003168316,0.00002306088,0.00006003632,0.00004113404,0.0000534399],"domain_scores_gemma":[0.9993225,0.000171787,0.0001721341,0.00004335718,0.00003777585,0.0002524444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9415816,0.007632241,0.007553556,0.0003746642,0.001388416,0.00006425818,0.0000690628,0.00097221,0.006212477,0.00008217006,0.001917079,0.03215232],"study_design_scores_gemma":[0.6519331,0.2959494,0.04386324,0.00007849277,0.001796598,0.0002175428,0.00006385837,0.002177545,0.002086125,0.0002373649,0.001563477,0.00003330507],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960069,0.001978283,0.0001224,0.0001786698,0.00006358152,0.0002747871,0.0005878421,0.00002790426,0.0007596578],"genre_scores_gemma":[0.9971282,0.0005578136,0.0002105871,0.0003188853,0.00009919825,0.0002513981,0.0009551218,0.000006124499,0.0004725984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002615329,"threshold_uncertainty_score":0.00890255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006136237237894708,"score_gpt":0.2507294225807201,"score_spread":0.2445931853428254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}