{"id":"W2774010325","doi":"10.1097/00007890-201407151-01253","title":"A New Model of Pure Acute Antibody-Mediated Rejection Shows Concurrent Complement-Mediated Injurious and Anti-Inflammatory Effects of High Titer Anti-MHC IgG DSA.","year":2014,"lang":"en","type":"article","venue":"Transplantation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Antibody; Medicine; Immunology; Transplantation; Immunoglobulin G; Peritubular capillaries; Kidney; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004446325,0.001269355,0.0006587559,0.00156591,0.0003535481,0.0006614209,0.000725436,0.0007393806,0.002805584],"category_scores_gemma":[0.0001401998,0.000328433,0.0005581478,0.0005439247,0.0005610352,0.0006958303,0.0005020911,0.001980057,0.0008960236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003494839,"about_ca_system_score_gemma":0.0004036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000520647,"about_ca_topic_score_gemma":0.0008939247,"domain_scores_codex":[0.9995633,0.00005354604,0.00004824296,0.0001172231,0.0001242921,0.00009334723],"domain_scores_gemma":[0.9996281,0.00003413251,0.00009013952,0.00006325761,0.00002824877,0.0001562194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0006881676,0.0006248926,0.0004969361,0.0001082229,0.00002144133,0.000270961,0.00003615257,0.00009289704,0.9947551,0.0003839801,0.0002838442,0.00223733],"study_design_scores_gemma":[0.0005265006,0.01597592,0.01558437,0.00007869093,0.0002009999,0.007546342,0.0001209323,0.002288035,0.9410748,0.0006444022,0.01589749,0.00006151304],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9693688,0.002624136,0.02021749,0.0004015393,0.0003117409,0.0004564,0.002814087,0.0006856107,0.003120197],"genre_scores_gemma":[0.9474268,0.003251569,0.02821083,0.0004573238,0.0001160763,0.0009069401,0.004915651,0.0001473731,0.01456738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002805584,"threshold_uncertainty_score":0.009385645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01262382654531312,"score_gpt":0.291068377895724,"score_spread":0.2784445513504109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}