{"id":"W2774477839","doi":"10.1089/scd.2017.0213","title":"Cell Clusters Are Indicative of Stem Cell Activity in the Degenerate Intervertebral Disc: Can Their Properties Be Manipulated to Improve Intrinsic Repair of the Disc?","year":2017,"lang":"en","type":"review","venue":"Stem Cells and Development","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Krembil Foundation","funders":"University of Sydney","keywords":"Stem cell; Biology; Intervertebral disc; Cell biology; Progenitor cell; Notochord; Population; CD90; Extracellular matrix; Pathology; Stem cell marker; Anatomy; Medicine; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004899571,0.0005281004,0.001787819,0.0001867848,0.0001255101,0.00002816707,0.000584543,0.0002422995,0.000007664449],"category_scores_gemma":[0.000009131763,0.0002343741,0.0004008625,0.0001980629,0.0002026571,0.00005916564,0.0006566605,0.0004652295,0.000004807582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000181703,"about_ca_system_score_gemma":0.0005543024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001758076,"about_ca_topic_score_gemma":0.0003906945,"domain_scores_codex":[0.9974318,0.0004155082,0.000965475,0.0005661078,0.0002798904,0.0003411899],"domain_scores_gemma":[0.9972811,0.00002327884,0.001661299,0.0008414848,0.00008952889,0.0001033009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001529018,0.001019307,0.001275975,0.06217452,0.0006790201,0.00007236195,0.02438014,0.000001760349,0.001844107,0.00001414328,0.001724856,0.9066609],"study_design_scores_gemma":[0.007823501,0.005194013,0.1065404,0.1235275,0.003188979,0.000198072,0.03551397,0.0001091956,0.4574107,0.0000117996,0.2564726,0.004009311],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4427445,0.5505959,0.00001595024,0.0002797253,0.0005490719,0.004639941,0.0002098645,0.0000258809,0.0009391802],"genre_scores_gemma":[0.8057256,0.1908727,0.00008778494,0.0002561116,0.00004390497,0.0003339204,0.00002756068,0.00006232001,0.002590092],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9026516,"threshold_uncertainty_score":0.9557499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1046448032010149,"score_gpt":0.2994519606267482,"score_spread":0.1948071574257333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}