{"id":"W2774526333","doi":"10.1016/j.bcp.2017.12.009","title":"The interaction of IGF-1/IGF-1R and hydrogen sulfide on the proliferation of mouse primary vascular smooth muscle cells","year":2017,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences North; Laurentian University","funders":"Canadian Institutes of Health Research; Health Canada; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Sodium hydrosulfide; Vascular smooth muscle; Cell growth; Bromodeoxyuridine; Growth factor; Western blot; Signal transduction; Insulin-like growth factor; Chemistry; Cell biology; Receptor; Internal medicine; Endocrinology; Biology; Molecular biology; Biochemistry; Hydrogen sulfide; Medicine; Smooth muscle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003691919,0.0001534439,0.0001897773,0.00002335195,0.0002242522,0.00001737806,0.0005008162,0.0002007065,0.00001649427],"category_scores_gemma":[0.0002520344,0.00009997915,0.00010424,0.00002603154,0.000709041,0.000006858292,0.0003143795,0.0001693201,0.000003841877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000240552,"about_ca_system_score_gemma":0.00006232281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001593671,"about_ca_topic_score_gemma":0.000002130119,"domain_scores_codex":[0.9988999,0.0001805548,0.0002953825,0.0003090786,0.0001070586,0.0002080239],"domain_scores_gemma":[0.998769,0.0001842218,0.0003147737,0.0005526199,0.0001296966,0.00004971371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000317087,0.00009711814,0.0001586541,0.00001790018,0.0001106908,5.820829e-7,0.00002131758,0.00001057481,0.985262,0.00008904909,0.01336221,0.0005528551],"study_design_scores_gemma":[0.0005737983,0.0002462817,0.0008288401,0.000005861076,0.00004515742,0.000002324528,0.00002434067,0.00008789042,0.9790988,0.00009580432,0.01888976,0.0001011708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971604,0.0008368044,0.00003195757,0.000865292,0.0003121319,0.0003404713,0.00001669638,0.00000663137,0.0004296694],"genre_scores_gemma":[0.9981803,0.0006891346,0.00007519232,0.0006259041,0.0002495472,0.00004921856,0.00003138899,0.00001636048,0.00008292815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006163193,"threshold_uncertainty_score":0.4077032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0157383091976821,"score_gpt":0.2805215705308201,"score_spread":0.264783261333138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}