{"id":"W2774774556","doi":"10.1096/fj.201700384rr","title":"Hypertension‐evoked RhoA activity in vascular smooth muscle cells requires RGS5","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heart and Stroke Foundation; Canadian Heart Research Centre; University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; Deutsche Forschungsgemeinschaft","keywords":"RHOA; Vascular smooth muscle; Smooth muscle; Medicine; Chemistry; Cardiology; Internal medicine; Cell biology; Neuroscience; Biology; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006987039,0.0001263828,0.0001377248,0.00003979768,0.0006004865,0.0001352359,0.0003860623,0.0001012397,0.0000475604],"category_scores_gemma":[0.000126546,0.00008829143,0.0001443695,0.00003105047,0.0001240431,0.00001496186,0.0001371397,0.0002258142,0.00001265087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001966211,"about_ca_system_score_gemma":0.00008131756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005816167,"about_ca_topic_score_gemma":0.00004045105,"domain_scores_codex":[0.9990743,0.0001467103,0.0001667731,0.0001818335,0.000187737,0.0002425799],"domain_scores_gemma":[0.999036,0.00001178333,0.000201679,0.0005899106,0.00006618767,0.00009445351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005132277,0.0000400859,0.0002125717,0.000004037685,0.00002038756,0.00003531127,0.00002651426,0.0002225695,0.989927,0.00001750561,0.0002538407,0.009188844],"study_design_scores_gemma":[0.001003138,0.00007410486,0.04393774,0.0000490088,0.00002093697,0.00002695735,0.00004074878,0.0006178,0.9459544,0.0003654901,0.007735953,0.000173727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970471,0.0005645214,0.000918274,0.000578467,0.0002140972,0.0001193534,0.00000404509,0.000005553501,0.0005486181],"genre_scores_gemma":[0.9987453,0.0002882524,0.0002016519,0.0001749192,0.0003804539,0.000004221756,0.000003483913,0.00001578874,0.0001859667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04397261,"threshold_uncertainty_score":0.4618517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02184332102007693,"score_gpt":0.2509820040811504,"score_spread":0.2291386830610735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}