{"id":"W2775364783","doi":"10.1007/s10549-017-4594-9","title":"CD14+ HLA-DR−/low MDSCs are elevated in the periphery of early-stage breast cancer patients and suppress autologous T cell proliferation","year":2017,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences North","funders":"Eberhard Karls Universität Tübingen; Deutsche Forschungsgemeinschaft","keywords":"CD14; Breast cancer; Medicine; Myeloid; Immune system; Cancer; Immunology; Immunotherapy; T cell; Internal medicine; Oncology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001033048,0.0002417119,0.0003375711,0.0006379745,0.0002575932,0.0004090175,0.0001315894,0.0002546983,0.002986207],"category_scores_gemma":[0.0004889211,0.0002381079,0.000117801,0.0002419298,0.0001503078,0.0001662703,0.0002208414,0.000402147,0.0004458557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000106773,"about_ca_system_score_gemma":0.0001251944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002362234,"about_ca_topic_score_gemma":0.0003313595,"domain_scores_codex":[0.9998953,0.00002535848,0.00001066496,0.00002224715,0.00001961726,0.00002679383],"domain_scores_gemma":[0.9998149,0.00003415898,0.00006892891,0.00001359001,0.00002057461,0.00004787145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006365118,0.0004751589,0.5912276,0.0002023891,0.0001320903,0.001957483,0.0003505522,0.0002770313,0.3486427,0.0003015762,0.001900243,0.04816798],"study_design_scores_gemma":[0.0001589334,0.001108594,0.9668646,0.00004410783,0.0001583623,0.004413699,0.0005896522,0.001128421,0.02121512,0.0005028434,0.003795163,0.00002061687],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986088,0.0004610279,0.0001597258,0.00004296695,0.00001154187,0.00001240405,0.0001720269,0.00001745899,0.0005140526],"genre_scores_gemma":[0.9984908,0.0001635682,0.0001831842,0.00006061155,0.00003387959,0.00002328588,0.0002607419,0.000007374997,0.0007764592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002986207,"threshold_uncertainty_score":0.009989798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0304616587200753,"score_gpt":0.3222820915742249,"score_spread":0.2918204328541497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}