{"id":"W2775577815","doi":"10.1007/s10549-017-4604-y","title":"A multi-center pragmatic, randomized, feasibility trial comparing standard of care schedules of filgrastim administration for primary febrile neutropenia prophylaxis in early-stage breast cancer","year":2017,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Neutropenia and Cancer Infections","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Grand River Hospital; Ottawa Hospital; University of Ottawa","funders":"European Society for Medical Oncology; Ottawa Hospital Research Institute","keywords":"Medicine; Filgrastim; Febrile neutropenia; Discontinuation; Randomized controlled trial; Breast cancer; Neutropenia; Randomization; Chemotherapy; Internal medicine; Clinical endpoint; Surgery; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000482489,0.0002231726,0.001094762,0.0001698308,0.0002897707,0.00008613562,0.0001319153,0.00008423949,0.00007774414],"category_scores_gemma":[0.00005175135,0.0001608666,0.0002020067,0.0001104439,0.0005757218,0.000185688,0.0000835875,0.0001869093,7.220645e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008628648,"about_ca_system_score_gemma":0.001277171,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01440389,"about_ca_topic_score_gemma":0.01909899,"domain_scores_codex":[0.9980061,0.0001859046,0.0005265066,0.0004469531,0.0004472448,0.0003872568],"domain_scores_gemma":[0.9981543,0.000136823,0.00029026,0.0005109188,0.0007096374,0.0001979916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6419536,0.001596461,0.3451248,0.0009787438,0.000276745,0.00001072421,0.0004036819,0.000009533456,0.0006419958,0.00009289664,0.000009986552,0.00890092],"study_design_scores_gemma":[0.5173421,0.004090371,0.4743678,0.0007326668,0.0001426023,0.00001959906,0.0002187575,0.00007184315,0.002791317,0.0000213572,0.00007790133,0.0001237287],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875306,0.0006860623,0.0000401303,0.000658251,0.0001362588,0.007115119,0.003654111,0.00001187514,0.0001675897],"genre_scores_gemma":[0.995061,0.0006384446,0.0004385227,0.000004517359,0.0001446861,0.00343901,0.00007396934,0.0000247463,0.000175055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.129243,"threshold_uncertainty_score":0.9987999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08349081564704279,"score_gpt":0.4204643519534432,"score_spread":0.3369735363064004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}