{"id":"W2775732789","doi":"10.24870/cjb.2017-a212","title":"Inferring the function of genes based on recurrent mutations in protein domains: Analysis of OncoMD data","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Biotechnology","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Gene; Genetics; Function (biology); Computational biology; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027628,0.00005482789,0.0001443552,0.0004216651,0.00009968811,0.00001179052,0.0006234305,0.0001350185,0.00001262678],"category_scores_gemma":[0.0002125975,0.0000428717,0.00006145352,0.0001882962,0.0002029895,0.000006137028,0.00003069964,0.000119003,2.175477e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002968506,"about_ca_system_score_gemma":0.0004369027,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001720277,"about_ca_topic_score_gemma":0.06310258,"domain_scores_codex":[0.999437,0.00003361877,0.0002636175,0.0001118092,0.00005798023,0.00009597762],"domain_scores_gemma":[0.9985746,0.000007163104,0.0004246884,0.0008624551,0.00008784766,0.00004328023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000185844,0.0001295026,0.02778464,0.00003284549,0.0009436734,0.00001520637,0.0000812888,0.01228056,0.6627358,0.003034318,0.0003215216,0.2924548],"study_design_scores_gemma":[0.002105319,0.002099782,0.3183639,0.000282295,0.001064804,0.0000183702,0.0008414893,0.01318661,0.5648217,0.0007412049,0.09606774,0.0004067741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924424,0.0007991455,0.004474165,0.001915099,0.0000828445,0.00008842472,0.00009773714,8.024727e-7,0.00009941899],"genre_scores_gemma":[0.9995038,0.0000777398,0.0003161738,0.00002618394,0.00002323482,0.000003357211,0.00003774776,0.000004264479,0.000007521861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.292048,"threshold_uncertainty_score":0.9539934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03249628111303491,"score_gpt":0.2881882103797739,"score_spread":0.2556919292667389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}