{"id":"W2775782243","doi":"10.15698/cst2017.12.115","title":"Protein quality control meets transcriptome remodeling under stress","year":2017,"lang":"en","type":"letter","venue":"Cell Stress","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Transcriptome; Cell biology; Protein quality; Protein folding; Stress (linguistics); Protein aggregation; Protein stability; Protein degradation; Chemistry; Biology; Biochemistry; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009757929,0.0003343044,0.0004519626,0.0001836378,0.0007539173,0.001214438,0.0004614545,0.006241271,0.003350298],"category_scores_gemma":[0.002998692,0.0001817381,0.000281704,0.0001761083,0.001879235,0.001036665,0.0007927294,0.004867434,0.003442138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001519503,"about_ca_system_score_gemma":0.0003897077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002287447,"about_ca_topic_score_gemma":0.0003700469,"domain_scores_codex":[0.9993605,0.0001275903,0.00006591957,0.0001124268,0.0002230905,0.0001104804],"domain_scores_gemma":[0.9983936,0.0006164936,0.0002457384,0.0002195995,0.0002648992,0.0002596404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001202187,0.0001633605,0.004118351,0.0006303304,0.00007030988,0.03286511,0.0003523755,0.000810409,0.09521553,0.05829766,0.6503558,0.1559186],"study_design_scores_gemma":[0.0002719223,0.0003571465,0.004779081,0.000150138,0.00003593758,0.02234172,0.0003090914,0.003369538,0.02586828,0.06564288,0.8768254,0.00004873319],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.02933956,0.03209339,0.005268834,0.8778373,0.03151762,0.00005050329,0.0001760621,0.0004272777,0.02328943],"genre_scores_gemma":[0.4185596,0.0335691,0.004141458,0.411688,0.08657275,0.0001860512,0.0002577683,0.0001583981,0.04486691],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.006241271,"threshold_uncertainty_score":0.01120782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0296149955619089,"score_gpt":0.3019144010590329,"score_spread":0.2722994054971241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}