{"id":"W2775782243","doi":"10.15698/cst2017.12.115","title":"Protein quality control meets transcriptome remodeling under stress","year":2017,"lang":"en","type":"letter","venue":"Cell Stress","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Transcriptome; Cell biology; Protein quality; Protein folding; Stress (linguistics); Protein aggregation; Protein stability; Protein degradation; Chemistry; Biology; Biochemistry; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003549246,0.0004854301,0.0005337562,0.0000768055,0.0002903323,0.0002263887,0.001099175,0.001242151,0.00005308532],"category_scores_gemma":[0.00008381637,0.000452009,0.0003375627,0.00003174957,0.0001823963,0.000008263287,0.0001278221,0.001262281,0.0000279805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004237119,"about_ca_system_score_gemma":0.0002125239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004702333,"about_ca_topic_score_gemma":0.0001142026,"domain_scores_codex":[0.9968441,0.0003246205,0.0004403673,0.0009371266,0.000570611,0.0008831742],"domain_scores_gemma":[0.9978027,0.0000314268,0.0003039926,0.001482864,0.0002048131,0.0001742023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001243646,0.00006311923,0.00008106484,0.0007569516,0.0001437735,0.0001309972,0.00001777326,0.000204441,0.8641805,0.000007097537,0.133725,0.0005649607],"study_design_scores_gemma":[0.003119134,0.0002844534,0.0001486916,0.0005902113,0.00009661086,0.000009423045,0.0000746048,0.0004329275,0.4864304,0.0001044834,0.5073095,0.001399555],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7429928,0.008591217,0.008806996,0.2160885,0.001159662,0.003393728,0.003393168,0.0001173184,0.01545655],"genre_scores_gemma":[0.8874084,0.000229718,0.0002017222,0.04391844,0.004991475,0.0001433703,0.002456733,0.0001777461,0.06047239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3777501,"threshold_uncertainty_score":0.9997932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0296149955619089,"score_gpt":0.3019144010590329,"score_spread":0.2722994054971241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}