{"id":"W2775851219","doi":"10.1097/pai.0000000000000626","title":"Hematoxylin and Eosin Counterstaining Protocol for Immunohistochemistry Interpretation and Diagnosis","year":2017,"lang":"en","type":"article","venue":"Applied immunohistochemistry & molecular morphology","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Immunohistochemistry; H&E stain; Pathology; Staining; Histopathology; Immunostaining; Medicine; Nuclear medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002792511,0.0004262514,0.0003775637,0.00004104786,0.0006703516,0.0001238008,0.000574798,0.0005196947,0.00001563963],"category_scores_gemma":[0.000182908,0.0004771393,0.0001301377,0.00003276272,0.000889753,0.00000984726,0.0005290351,0.0002340452,0.000002094871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005311343,"about_ca_system_score_gemma":0.00007741861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000252359,"about_ca_topic_score_gemma":2.235959e-7,"domain_scores_codex":[0.9980073,0.00002775705,0.0004465365,0.000974051,0.0001078235,0.0004365064],"domain_scores_gemma":[0.9979147,0.00003028525,0.0004697731,0.001331855,0.0001279215,0.0001254452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003701417,0.00006821058,0.0001968453,0.0001156817,0.00008901288,0.000007631413,0.00003500281,0.00000194116,0.9944525,0.0009400202,0.001300713,0.002422296],"study_design_scores_gemma":[0.002005367,0.0002212575,0.0002952254,0.00004639934,0.0000620659,0.0002101387,0.00007504347,0.00006316835,0.9881133,0.001025753,0.007331301,0.0005509854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9010068,0.000803772,0.05774555,0.0006732094,0.00007088177,0.03535505,0.00008671607,0.00009434618,0.004163677],"genre_scores_gemma":[0.8003041,0.00004344041,0.007809339,0.0004485508,0.00006059705,0.1908496,0.0002409629,0.00006709949,0.0001763711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1554945,"threshold_uncertainty_score":0.999768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116052988484554,"score_gpt":0.3299900108188495,"score_spread":0.318829480934004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}