{"id":"W2776100553","doi":"10.1161/atvb.37.suppl_1.407","title":"Abstract 407: High Density Lipoprotein Mediated Protection of Macrophages Against Apoptosis Requires Scavenger Receptor Class B Type 1 Activity and Sphingosine-1-Phosphate","year":2017,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"S1PR1; Scavenger receptor; Apoptosis; Sphingosine-1-phosphate; Cell biology; TUNEL assay; Sphingosine-1-phosphate receptor; Macrophage; Receptor; Sphingosine; Biology; Chemistry; Lipoprotein; Cancer research; Biochemistry; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001833891,0.0004810102,0.000285303,0.0002021077,0.0001913393,0.00023577,0.0002627934,0.0005228369,0.006138386],"category_scores_gemma":[0.0001388955,0.0001252864,0.0003413579,0.0001627258,0.0002313873,0.0002816315,0.0001905263,0.0005690056,0.0019915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000236812,"about_ca_system_score_gemma":0.0002931276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002462577,"about_ca_topic_score_gemma":0.0002146175,"domain_scores_codex":[0.9998612,0.00002038183,0.00001540101,0.0000233867,0.0000462412,0.00003330333],"domain_scores_gemma":[0.9998602,0.00002053898,0.00004094368,0.00001284227,0.00003804509,0.0000274273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006774584,0.00006548192,0.0003035399,0.0002447143,0.0000130052,0.0002064958,0.00001661178,0.00003498232,0.9944282,0.0002435337,0.0002666245,0.00349937],"study_design_scores_gemma":[0.0001641878,0.0009988382,0.01034892,0.00004221819,0.00004564143,0.00124951,0.00004223909,0.0005164628,0.9786553,0.0004002839,0.007530313,0.000006065402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9699935,0.01054809,0.007989992,0.001458238,0.0003270984,0.0001013762,0.001467542,0.0002748882,0.007839222],"genre_scores_gemma":[0.9700229,0.005432113,0.00395538,0.0003363979,0.000154653,0.0001118011,0.002468333,0.00003114565,0.01748731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006138386,"threshold_uncertainty_score":0.02053493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02494553026257717,"score_gpt":0.2645995645836495,"score_spread":0.2396540343210723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}