{"id":"W2776523889","doi":"10.1212/wnl.88.16_supplement.s24.008","title":"Efficacy and Safety of Ozanimod: Results From the 2-Year Blinded Extension of RADIANCE, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial in Relapsing Multiple Sclerosis (S24.008)","year":2017,"lang":"en","type":"article","venue":"Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; NeuroRx Research (Canada)","funders":"","keywords":"Medicine; Placebo; Radiance; Multiple sclerosis; Double blind; Randomized controlled trial; Physical therapy; Internal medicine; Pathology; Alternative medicine; Psychiatry; Remote sensing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00427303,0.001904781,0.003093831,0.0005956613,0.0005099727,0.0008547042,0.001090012,0.002481881,0.005075963],"category_scores_gemma":[0.002579076,0.0006562018,0.00190038,0.0004435471,0.001188531,0.001683065,0.0004507468,0.002761081,0.000982007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005915973,"about_ca_system_score_gemma":0.001195386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007687986,"about_ca_topic_score_gemma":0.001806363,"domain_scores_codex":[0.9985934,0.0008538468,0.0001012754,0.0001594088,0.0001119336,0.0001801052],"domain_scores_gemma":[0.9981817,0.0004203663,0.0005640495,0.0001775271,0.0001500037,0.0005063021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9715183,0.008041183,0.0005581958,0.0004162576,0.0005278666,0.00002480852,0.00005175997,0.0001314848,0.005623421,0.00004451371,0.0004179323,0.01264422],"study_design_scores_gemma":[0.8488158,0.1449696,0.004055637,0.00002417588,0.0004491768,0.0000363696,0.00001987842,0.0001420946,0.0008948708,0.00005568511,0.0005177063,0.00001892938],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878671,0.005282731,0.0006641829,0.000459767,0.0002385806,0.002298984,0.001484466,0.0001514542,0.00155271],"genre_scores_gemma":[0.9853114,0.002960642,0.002169588,0.0009832719,0.0005429817,0.002648902,0.002581963,0.00004985263,0.002751473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005075963,"threshold_uncertainty_score":0.02259821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1348058916143419,"score_gpt":0.3615046640751763,"score_spread":0.2266987724608344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}