{"id":"W2776608992","doi":"10.3390/v9120387","title":"The Influence of E1A C-Terminus on Adenovirus Replicative Cycle","year":2017,"lang":"en","type":"article","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Research Manitoba","keywords":"Exon; Biology; Viral replication; Gene; Viral life cycle; Adenovirus genome; RNA splicing; Molecular biology; Adenovirus infection; Adenoviridae; Alternative splicing; Genetics; Genome; Virus; RNA; Genetic enhancement","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417435,0.0001116922,0.0001024349,0.00002165218,0.0004281471,0.00005734456,0.0008516152,0.00007269298,0.00001029348],"category_scores_gemma":[0.0003853635,0.00007906558,0.00005867636,0.00002989331,0.0004440372,0.000006215834,0.0002055998,0.00009362184,0.0000619132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009527073,"about_ca_system_score_gemma":0.00007384375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001101517,"about_ca_topic_score_gemma":0.000225192,"domain_scores_codex":[0.9991026,0.00006660384,0.0001544045,0.0002761041,0.0001821184,0.0002181873],"domain_scores_gemma":[0.9980183,0.00004965719,0.0001751593,0.001603522,0.00009833959,0.00005503664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001447568,0.00004663318,0.001948841,0.00000485277,0.00004979139,0.000003983738,0.00002561215,0.00009941539,0.9820048,0.0001474316,0.0006695929,0.01355151],"study_design_scores_gemma":[0.0002830634,0.001660223,0.02182566,0.00001374588,0.000004389646,0.000001793832,0.00001368984,0.000004620135,0.9521865,0.000175777,0.023732,0.00009850945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975571,0.0004695031,0.000002785882,0.0002170697,0.00004086536,0.0001652551,0.00003241975,0.000007608856,0.001507384],"genre_scores_gemma":[0.9984987,0.0005313812,0.00001802281,0.0003831077,0.00009940843,0.00003856319,0.000002654295,0.00001861438,0.0004095299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02981824,"threshold_uncertainty_score":0.3293004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03077589043322362,"score_gpt":0.3545022357133294,"score_spread":0.3237263452801058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}