{"id":"W2777050540","doi":"10.1093/eurheartj/ehy474","title":"A comprehensive evaluation of the genetic architecture of sudden cardiac arrest","year":2018,"lang":"en","type":"review","venue":"European Heart Journal","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; Sociale en Geesteswetenschappen, NWO; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Human Genome Research Institute; National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health; National Institute of General Medical Sciences; Fondation Institut de Cardiologie de Montréal; Center for Translational Molecular Medicine; Sydäntutkimussäätiö; Erasmus Medisch Centrum; Bundesministerium für Bildung und Forschung; Institut de Cardiologie de Montréal; Novo Nordisk Fonden; Academy of Finland; National Research Foundation; National Center for Research Resources; Agence Nationale de la Recherche; Fondation Leducq; School of Medicine, Boston University; European Commission; College ter Beoordeling van Geneesmiddelen; US-UK Fulbright Commission; Foundation for Cardiovascular Research; Rigshospitalet; ZonMw; Institut National de la Santé et de la Recherche Médicale; Danmarks Grundforskningsfond; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; U.S. Department of Agriculture","keywords":"Medicine; Sudden cardiac arrest; Genetic architecture; Sudden cardiac death; Cardiology; Internal medicine; Intensive care medicine; Environmental health; Population","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001292278,0.0004832407,0.0003958726,0.001697885,0.0003558813,0.000377019,0.0002463791,0.0003347694,0.00111551],"category_scores_gemma":[0.001730153,0.0001470408,0.0004428802,0.001227348,0.0003100735,0.00029409,0.0006019753,0.0002833917,0.0001349984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001487148,"about_ca_system_score_gemma":0.0004465205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001698248,"about_ca_topic_score_gemma":0.003170266,"domain_scores_codex":[0.9994017,0.000194407,0.00006176448,0.0001872047,0.0001116173,0.00004329615],"domain_scores_gemma":[0.9991012,0.000269862,0.0002434327,0.0001016884,0.0001651478,0.0001186445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003683039,0.00007827804,0.9481425,0.0001627435,0.001124061,0.0008794413,0.0001934633,0.001345824,0.01216663,0.0003320161,0.0005562755,0.03465042],"study_design_scores_gemma":[0.00001859088,0.0002254005,0.9960102,0.00002773876,0.0002983305,0.001070182,0.00006799775,0.000728063,0.0004369165,0.0003188682,0.0007889453,0.000008750468],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9923242,0.002546004,0.00310933,0.0001893903,0.00001494008,0.0000331682,0.0008939045,0.0000433695,0.0008456271],"genre_scores_gemma":[0.9954684,0.001052959,0.00214432,0.00005900761,0.00003490359,0.00001845068,0.0009991471,0.000009720666,0.0002131479],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001698248,"threshold_uncertainty_score":0.006834269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0882975408237558,"score_gpt":0.3634712702075116,"score_spread":0.2751737293837558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}