{"id":"W2777288228","doi":"10.1200/jco.2013.31.15_suppl.2005","title":"Progression-free survival (PFS) and health-related quality of life (HRQoL) in AVAglio, a phase III study of bevacizumab (Bv), temozolomide (T), and radiotherapy (RT) in newly diagnosed glioblastoma (GBM).","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Temozolomide; Internal medicine; Bevacizumab; Clinical endpoint; Discontinuation; Quality of life (healthcare); Placebo; Progression-free survival; Toxicity; Oncology; Gastroenterology; Radiation therapy; Randomized controlled trial; Surgery; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004362322,0.00118098,0.001828663,0.00037756,0.0003366962,0.0008837395,0.0007894604,0.001404052,0.00200171],"category_scores_gemma":[0.001969136,0.0006035296,0.001804257,0.0003893857,0.0008133701,0.0008142457,0.0004531377,0.004054442,0.0003864224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008820053,"about_ca_system_score_gemma":0.001374733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001229621,"about_ca_topic_score_gemma":0.002832161,"domain_scores_codex":[0.9989793,0.0006551062,0.00004538396,0.0001113353,0.00006928547,0.0001395857],"domain_scores_gemma":[0.9983955,0.0004471068,0.0003660504,0.00008286592,0.0001036423,0.0006047301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9291937,0.02974712,0.006597668,0.000379344,0.001129566,0.00004454316,0.0001018645,0.0008482349,0.004624769,0.00007163049,0.001115024,0.02614645],"study_design_scores_gemma":[0.5668861,0.4034087,0.02359079,0.00003901058,0.00150636,0.00007726954,0.0000419066,0.001444223,0.001726139,0.0001498136,0.001107243,0.00002236426],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946896,0.002668469,0.0002932624,0.0002885788,0.0001031959,0.0006616799,0.0005645956,0.00003345024,0.0006972848],"genre_scores_gemma":[0.9950482,0.001109962,0.0006563254,0.0003821013,0.0001632201,0.0009978466,0.0008122433,0.00001133427,0.0008187611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004362322,"threshold_uncertainty_score":0.02307039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1143641771653012,"score_gpt":0.4844240312089672,"score_spread":0.3700598540436659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}