{"id":"W2778570670","doi":"10.1165/rcmb.2017-0316le","title":"Hypercapnic Acidosis Regulates Mer Tyrosine Kinase Receptor Shedding and Activity","year":2017,"lang":"en","type":"letter","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Tyrosine kinase; Acidosis; Receptor tyrosine kinase; Receptor; ROR1; Chemistry; Pharmacology; Endocrinology; Internal medicine; Biology; Medicine; Platelet-derived growth factor receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000275465,0.0002609956,0.0003737628,0.00009326957,0.0003610663,0.0006267736,0.0002464092,0.001826492,0.003216328],"category_scores_gemma":[0.0006862496,0.0001420148,0.0002569788,0.00008624498,0.0003913875,0.0004138219,0.0002713633,0.002269605,0.000817065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005075894,"about_ca_system_score_gemma":0.0002032023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002277354,"about_ca_topic_score_gemma":0.0003109871,"domain_scores_codex":[0.9998307,0.00003506189,0.00001563805,0.00002256003,0.00005261506,0.00004339135],"domain_scores_gemma":[0.9996878,0.000153367,0.00003221701,0.00004187005,0.00004039858,0.00004437949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02679909,0.001326624,0.03813989,0.0003876025,0.0001576287,0.08193973,0.0008122894,0.0008814526,0.5703907,0.01116324,0.1436735,0.1243283],"study_design_scores_gemma":[0.001766105,0.003563998,0.1898637,0.0001802984,0.0001965481,0.05823205,0.001795457,0.008757495,0.4293611,0.01780588,0.2883292,0.0001480589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.802381,0.01182742,0.002723398,0.1399594,0.01190504,0.0001033705,0.0006627444,0.0003760947,0.03006152],"genre_scores_gemma":[0.9687824,0.002091112,0.0005073128,0.01160509,0.004375333,0.00006209525,0.0001512072,0.00003143076,0.01239407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003216328,"threshold_uncertainty_score":0.01075971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01071922079079444,"score_gpt":0.2522504604303893,"score_spread":0.2415312396395949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}