{"id":"W2778781711","doi":"10.1007/978-3-319-67577-0_14","title":"Adaptive Resistance to Cancer Immunotherapy","year":2017,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Immune system; Immunotherapy; Tumor microenvironment; Immunosuppression; Acquired immune system; Cancer immunotherapy; Biology; Immunology; Cancer; Cancer research; Immune tolerance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007627488,0.0009430436,0.001321313,0.001234472,0.0002177571,0.001314871,0.0007603289,0.001117565,0.004182272],"category_scores_gemma":[0.001119626,0.0002307825,0.0004282017,0.0008849899,0.0006261333,0.001216504,0.001051555,0.002762694,0.001905546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005652108,"about_ca_system_score_gemma":0.001052799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003241533,"about_ca_topic_score_gemma":0.0006676816,"domain_scores_codex":[0.9997247,0.00006554865,0.00003098662,0.00004709124,0.00008969193,0.00004190855],"domain_scores_gemma":[0.999656,0.0001761428,0.00004534679,0.00001683769,0.00007377793,0.00003192217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001028928,0.00007116133,0.0001991407,0.011067,0.00007946793,0.0001739811,0.00004730238,0.0004433173,0.002403994,0.00774435,0.04915632,0.9285111],"study_design_scores_gemma":[0.00003115636,0.00007280333,0.0003684871,0.002640056,0.00009780841,0.0006711151,0.00003331701,0.000143556,0.0007388373,0.003993824,0.991194,0.00001508429],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001414592,0.996099,0.0004791069,0.0008473936,0.0006357259,0.000009673585,0.00002465936,0.00001692411,0.001746081],"genre_scores_gemma":[0.001851847,0.9944879,0.0003837704,0.001146225,0.000762457,0.0000179252,0.0000629036,0.000003767189,0.001283296],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004182272,"threshold_uncertainty_score":0.01399112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1317773422897974,"score_gpt":0.4919744922433903,"score_spread":0.360197149953593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}