{"id":"W2779453443","doi":"10.1016/j.bbrc.2017.12.116","title":"Inhibition of CX3CR1 reduces cell motility and viability in pancreatic adenocarcinoma epithelial cells","year":2017,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Public Health Agency of Canada; Drexel University; Pharmaceutical Research and Manufacturers of America Foundation; W. W. Smith Charitable Trust; American Cancer Society","keywords":"CX3CR1; Motility; CX3CL1; Chemokine receptor; Cancer research; Pancreatic cancer; Metastasis; Downregulation and upregulation; Protein kinase B; Biology; Receptor; Chemokine; Internal medicine; Cancer; Medicine; Signal transduction; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001281205,0.0002620913,0.0003426534,0.0002097987,0.0002008369,0.0003132877,0.0001668883,0.0002163775,0.001355537],"category_scores_gemma":[0.0001121925,0.000129037,0.0002378375,0.0002058395,0.0001455046,0.000126421,0.0001414421,0.0006195115,0.0003199659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003138797,"about_ca_system_score_gemma":0.0004328646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002038618,"about_ca_topic_score_gemma":0.002878516,"domain_scores_codex":[0.9998042,0.00002915228,0.00001808978,0.00002294657,0.00006029403,0.00006528572],"domain_scores_gemma":[0.9999207,0.00001713141,0.00001359522,0.00001039487,0.0000100448,0.0000280938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003898536,0.000201512,0.0003215629,0.00006965582,0.00001159486,0.00005710469,0.00002606862,0.0001782004,0.9949213,0.00008692483,0.0002481215,0.003488065],"study_design_scores_gemma":[0.00007242987,0.002186094,0.01047324,0.00001183432,0.00002392044,0.0002326543,0.00006411609,0.002121808,0.9815083,0.00004077819,0.003258738,0.000006133934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946002,0.002053572,0.0004477538,0.0001575131,0.00004220882,0.00002334051,0.0003605009,0.00006794222,0.002246982],"genre_scores_gemma":[0.994137,0.001674104,0.0006142514,0.00007583014,0.00001074853,0.00004188705,0.0005754256,0.00001138625,0.002859151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002038618,"threshold_uncertainty_score":0.004534721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07424799531700298,"score_gpt":0.3666321043632756,"score_spread":0.2923841090462726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}