{"id":"W2779821553","doi":"10.3762/bjoc.13.281","title":"Acid-catalyzed ring-opening reactions of a cyclopropanated 3-aza-2-oxabicyclo[2.2.1]hept-5-ene with alcohols","year":2017,"lang":"en","type":"article","venue":"Beilstein Journal of Organic Chemistry","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Nucleophile; Cyclopropane; Alkene; Ring (chemistry); Catalysis; Pyridinium; Piperidine; Medicinal chemistry; Alcohol; Electrophile; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004350824,0.0004954141,0.0009074934,0.0001047909,0.0004886777,0.0002043346,0.001446858,0.000353908,0.002530763],"category_scores_gemma":[0.00098092,0.0004438594,0.0003324943,0.0002091004,0.0002767782,0.0006010101,0.0002584143,0.001090129,0.00001859185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004178702,"about_ca_system_score_gemma":0.0006255838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005471664,"about_ca_topic_score_gemma":0.00001604464,"domain_scores_codex":[0.9967291,0.00002502491,0.001335489,0.0004763729,0.0009100874,0.0005238976],"domain_scores_gemma":[0.9925303,0.00008684573,0.004556711,0.001577166,0.0008335441,0.0004154087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000329356,0.0001788646,0.00156903,0.000578222,0.0004109411,0.000268152,0.0002497321,0.00001397906,0.9932238,0.00001221462,0.00004607417,0.003119617],"study_design_scores_gemma":[0.003340209,0.00006296756,0.0004853741,0.0009503079,0.0003430843,0.003556506,0.001386045,0.00001672458,0.9874318,0.00007061724,0.001889053,0.0004673671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833702,0.0004884641,0.0005465016,0.0002374639,0.0001712692,0.0001075163,0.00002674124,0.00007812557,0.01497371],"genre_scores_gemma":[0.9953167,0.0001551008,0.002118157,0.000008911824,0.0004938367,0.000008074089,0.00002400828,0.0001283211,0.001746923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01322679,"threshold_uncertainty_score":0.9998013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01414771887379323,"score_gpt":0.2460394395510195,"score_spread":0.2318917206772263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}