{"id":"W2780021300","doi":"10.1002/pmic.201700285","title":"Importance of the RpoE Regulon in Maintaining the Lipid Bilayer during Antimicrobial Treatment with the Polycationic Agent, Chlorhexidine","year":2017,"lang":"en","type":"article","venue":"PROTEOMICS","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada; McMaster University; Brockhouse Institute for Materials Research; Canadian Light Source (Canada); University of Saskatchewan","funders":"","keywords":"Regulon; Microbiology; Antimicrobial; Mutant; Escherichia coli; Sigma factor; Biology; Population; rpoS; SOS response; Multiple drug resistance; Biofilm; Wild type; Bacteria; Chemistry; Biochemistry; Drug resistance; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001482904,0.0001999027,0.00014883,0.00007028241,0.00009762636,0.0002898808,0.0001075312,0.0002342312,0.0003057107],"category_scores_gemma":[0.0001838496,0.00008465405,0.0001228608,0.0000584857,0.0002339475,0.000193943,0.0001763344,0.0002444406,0.0001287358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001035055,"about_ca_system_score_gemma":0.0001409491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000322296,"about_ca_topic_score_gemma":0.0003038711,"domain_scores_codex":[0.9998727,0.00002351862,0.000009039089,0.00002606327,0.00004048134,0.00002810226],"domain_scores_gemma":[0.9998795,0.00002364449,0.00003718743,0.00001965296,0.00002270934,0.00001725647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002052045,0.000002653431,0.0001292159,0.000005769481,5.977748e-7,0.00001415207,0.00000733304,0.000009336515,0.9994811,0.00001056147,0.000001560111,0.000317249],"study_design_scores_gemma":[0.000002805408,0.00009333601,0.006281901,0.000003657164,0.000005074211,0.0001295555,0.00005577458,0.0003489341,0.9927073,0.00002989181,0.0003386209,0.000003184862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969447,0.0003563518,0.002231643,0.00005265456,0.000008082519,0.000007597663,0.00004420111,0.00001983057,0.0003348482],"genre_scores_gemma":[0.9974144,0.0002228906,0.001809739,0.00002140073,0.000003196565,0.000008724704,0.0000606533,0.00001065905,0.000448248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000322296,"threshold_uncertainty_score":0.001022696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00992873512766748,"score_gpt":0.2264174020720847,"score_spread":0.2164886669444172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}