{"id":"W2781002445","doi":"10.1002/bit.26523","title":"Engineered cell migration to lesions linked to autoimmune disease","year":2017,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Cancer Society Research Institute","keywords":"Autoimmune disease; Immunology; Multiple sclerosis; Rheumatoid arthritis; Cell; Granulocyte macrophage colony-stimulating factor; Chemotaxis; Secretion; Biology; Cancer research; Receptor; Cell biology; Medicine; Cytokine; Antibody; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001389621,0.0002352141,0.000249816,0.0003305746,0.0006159712,0.00005492495,0.0004538801,0.0004246709,0.00004904105],"category_scores_gemma":[0.0001950134,0.0002192337,0.00006350144,0.0001140379,0.0001353457,0.0001013512,0.0002456995,0.0002921495,0.0002503715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002535364,"about_ca_system_score_gemma":0.00002863855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005455381,"about_ca_topic_score_gemma":0.000006445711,"domain_scores_codex":[0.9989882,0.00002564283,0.0002218291,0.0003329394,0.00002527321,0.0004060957],"domain_scores_gemma":[0.999033,0.00004307261,0.00005860462,0.0007784195,0.00002877221,0.0000581313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002281106,0.00004439621,0.0001610387,0.00001686158,0.00005815901,0.0000107359,0.0001310537,0.00006599497,0.9801704,0.0006840414,0.0002839956,0.01814523],"study_design_scores_gemma":[0.0008972889,0.0003059917,0.1038897,0.00009979727,0.00004280113,0.00003719137,0.0001106894,0.00008854188,0.7146057,0.00002251439,0.1794443,0.0004554881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9785112,0.005539758,0.005528754,0.008832223,0.0007786693,0.0003687868,0.00002888138,0.0003531112,0.00005862367],"genre_scores_gemma":[0.9960701,0.0003743243,0.0008512181,0.0001376413,0.00002252692,0.00005380519,0.00001993642,0.00002505442,0.002445393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2655647,"threshold_uncertainty_score":0.894009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01077041916264445,"score_gpt":0.2272089703012881,"score_spread":0.2164385511386437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}