{"id":"W2781002445","doi":"10.1002/bit.26523","title":"Engineered cell migration to lesions linked to autoimmune disease","year":2017,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Cancer Society Research Institute","keywords":"Autoimmune disease; Immunology; Multiple sclerosis; Rheumatoid arthritis; Cell; Granulocyte macrophage colony-stimulating factor; Chemotaxis; Secretion; Biology; Cancer research; Receptor; Cell biology; Medicine; Cytokine; Antibody; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014078,0.0002891567,0.0001597904,0.0001447921,0.0001166522,0.0002570033,0.0001783965,0.0003114155,0.000806122],"category_scores_gemma":[0.00006863585,0.00008544243,0.0001636854,0.00007037194,0.0001542095,0.00008214681,0.0002078885,0.0003911691,0.0002673293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001904634,"about_ca_system_score_gemma":0.0001369727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003699307,"about_ca_topic_score_gemma":0.0003852124,"domain_scores_codex":[0.9999106,0.00001245916,0.000006245913,0.00001945452,0.00001801035,0.00003328986],"domain_scores_gemma":[0.9999378,0.00001390578,0.00001232014,0.000009897457,0.00001011734,0.00001598645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003481509,0.0000302219,0.00007744527,0.00001712051,0.000002180291,0.00004830947,0.00001989428,0.0002506871,0.9979028,0.0002949905,0.00004338179,0.00127818],"study_design_scores_gemma":[0.00001930998,0.000337765,0.0005893453,0.000006582552,0.00001013102,0.0001723833,0.00002115575,0.003537087,0.9910184,0.00006708436,0.004217014,0.000003818543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856616,0.0005683461,0.01086951,0.00008737024,0.00008105062,0.00004448184,0.0000775411,0.000131389,0.002478781],"genre_scores_gemma":[0.9910416,0.0002835618,0.00540129,0.00004833332,0.000007073065,0.00003020183,0.0000910124,0.0000200599,0.003076852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000806122,"threshold_uncertainty_score":0.002696753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01077041916264445,"score_gpt":0.2272089703012881,"score_spread":0.2164385511386437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}