{"id":"W2781013802","doi":"10.1177/1559325817748121","title":"Cytotoxic Profiling of Plant Secondary Metabolites on P53 Variant Human Colon Carcinoma Cell Lines","year":2017,"lang":"en","type":"article","venue":"Dose-Response","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"CANDU Owners Group; Bruce Power","keywords":"Cytotoxic T cell; Profiling (computer programming); Cancer research; Cell culture; Carcinoma Cell; Computational biology; Biology; Genetics; In vitro; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001097154,0.0003006596,0.000598701,0.000290504,0.000321358,0.00004888695,0.0003223243,0.0002329978,0.0001557044],"category_scores_gemma":[0.0007513757,0.0002696557,0.0002301149,0.0001004023,0.0001885789,0.00008348191,0.0001256332,0.0004692823,0.00006211537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001173637,"about_ca_system_score_gemma":0.0005745639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001317125,"about_ca_topic_score_gemma":0.00002053536,"domain_scores_codex":[0.9979364,0.0003189951,0.0004849854,0.0004689331,0.0003931061,0.0003975542],"domain_scores_gemma":[0.9976525,0.0002804887,0.0004089867,0.001310346,0.0001378203,0.000209878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02203812,0.0003006656,0.0009292485,0.0001671311,0.0000853146,0.001061067,0.0005587447,0.00001806282,0.9739557,0.0002185657,0.0004266101,0.0002407692],"study_design_scores_gemma":[0.004441582,0.001505783,0.1015961,0.0001957398,0.0001916862,0.0001262512,0.00008335237,0.000227731,0.8875217,0.00003453135,0.003838666,0.0002368747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953367,0.0008403091,0.00002129557,0.0004693336,0.0004109504,0.000876346,0.000441327,0.00007733057,0.001526478],"genre_scores_gemma":[0.9977847,0.00001794303,0.0005648624,0.0002144185,0.0001936014,0.00005763306,0.00008264929,0.00006958986,0.001014597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1006669,"threshold_uncertainty_score":0.9999756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02499651403697445,"score_gpt":0.2859012778306117,"score_spread":0.2609047637936373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}