{"id":"W2781013802","doi":"10.1177/1559325817748121","title":"Cytotoxic Profiling of Plant Secondary Metabolites on P53 Variant Human Colon Carcinoma Cell Lines","year":2017,"lang":"en","type":"article","venue":"Dose-Response","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"CANDU Owners Group; Bruce Power","keywords":"Cytotoxic T cell; Profiling (computer programming); Cancer research; Cell culture; Carcinoma Cell; Computational biology; Biology; Genetics; In vitro; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001189023,0.0002655922,0.0002146787,0.0004724739,0.0001729315,0.0001552051,0.00009132602,0.0001975124,0.001005293],"category_scores_gemma":[0.0001491021,0.00008019141,0.0001937554,0.0003808899,0.0001138129,0.00009337636,0.000114186,0.0002023614,0.0002898816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001309501,"about_ca_system_score_gemma":0.0001366231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001059589,"about_ca_topic_score_gemma":0.001873155,"domain_scores_codex":[0.9999001,0.0000278049,0.00001182121,0.00001752821,0.00002750829,0.00001525521],"domain_scores_gemma":[0.9998558,0.00003869439,0.00001991801,0.00002209838,0.00004818469,0.00001533717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001263228,0.00003370502,0.0006925763,0.00002974222,0.00000589426,0.00004048464,0.00001846611,0.0001079636,0.9979061,0.00001134161,0.00001834295,0.001009025],"study_design_scores_gemma":[0.000009276693,0.001288938,0.01582841,0.000006239052,0.00003222497,0.00019038,0.00006207842,0.0004305196,0.9814346,0.00001793612,0.0006947429,0.000004705111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960678,0.0009485288,0.001118483,0.00003197324,0.000009715282,0.00004431972,0.0008544305,0.0000245006,0.000900306],"genre_scores_gemma":[0.9928367,0.001547181,0.001790841,0.00004277057,0.00000815455,0.00008108551,0.001633264,0.00001176336,0.002048297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001059589,"threshold_uncertainty_score":0.003363013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02499651403697445,"score_gpt":0.2859012778306117,"score_spread":0.2609047637936373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}