{"id":"W2781512269","doi":"10.1038/s41467-017-02488-y","title":"GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Diet, Metabolism, and Disease","field":"Medicine","cited_by":188,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"Banting and Best Diabetes Centre, University of Toronto; Core Research for Evolutional Science and Technology; Japan Diabetes Foundation; Novo Nordisk; Ministry of Education, Culture, Sports, Science and Technology; Canadian Institutes of Health Research; Jichi Medical University; Japan Agency for Medical Research and Development","keywords":"Overeating; Glucagon-like peptide-1; Endocrinology; Internal medicine; Vagotomy; Vagus nerve; Medicine; Receptor; Diabetes mellitus; Obesity; Type 2 diabetes; Stimulation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001546606,0.0001237732,0.0002218227,0.00008605588,0.0002112044,0.00001877709,0.0002301141,0.0001447227,0.00001343123],"category_scores_gemma":[0.0003822489,0.00008396772,0.00004984062,0.0001962086,0.0004115332,0.00008022776,0.000144943,0.0003940642,0.000003240453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001160301,"about_ca_system_score_gemma":0.00008083339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002170859,"about_ca_topic_score_gemma":0.00006246784,"domain_scores_codex":[0.9992368,0.0001446616,0.000168927,0.0001465552,0.0001783114,0.0001247019],"domain_scores_gemma":[0.9982334,0.0003845698,0.0001070716,0.0009901751,0.0001691125,0.0001156411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.00270787,0.005094655,0.07192053,0.001415642,0.001940654,0.000007489309,0.01686077,0.000002701568,0.1395241,0.2632256,0.006649185,0.4906508],"study_design_scores_gemma":[0.00249947,0.0002047618,0.9328636,0.000132559,0.0009727511,0.000006874761,0.0002071555,0.0007142248,0.01331971,0.00101688,0.04789187,0.0001701629],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.938323,0.05560897,0.00003768706,0.004541309,0.0001500064,0.0005091072,0.00001468793,0.00003522547,0.0007800196],"genre_scores_gemma":[0.9906279,0.007222112,0.0003729577,0.001413594,0.0002363982,0.00003586127,0.00003746845,0.00001648899,0.00003724203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.860943,"threshold_uncertainty_score":0.3424104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01328359035210767,"score_gpt":0.3005602809310254,"score_spread":0.2872766905789177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}