{"id":"W2781575714","doi":"10.1097/pas.0000000000001010","title":"A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential","year":2018,"lang":"en","type":"article","venue":"The American Journal of Surgical Pathology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"National Cancer Institute","keywords":"Pathology; Biology; Fluorescence in situ hybridization; S100 protein; Myoepithelial cell; Fusion gene; Cytokeratin; Gene; Immunohistochemistry; Medicine; Chromosome; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007094952,0.000197872,0.0004222319,0.00005843912,0.0001670456,0.0000187122,0.0002493332,0.00003431182,0.00002162511],"category_scores_gemma":[0.00007186869,0.0001059852,0.00009097096,0.0001249579,0.001545479,0.000005323174,0.0001553408,0.0001674796,0.00000560785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001081953,"about_ca_system_score_gemma":0.00006950481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001103451,"about_ca_topic_score_gemma":0.000004711947,"domain_scores_codex":[0.99831,0.0005002714,0.000389561,0.0002669249,0.0002235779,0.0003096642],"domain_scores_gemma":[0.9987859,0.00004092489,0.0005300093,0.0002753681,0.0002393658,0.0001284295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001437287,0.00008727859,0.0008188575,0.000008241672,0.0001788028,0.001143681,0.0002524026,0.0000121127,0.9908642,0.00001400687,0.0001252529,0.0050579],"study_design_scores_gemma":[0.006063169,0.02272256,0.01837268,0.0002764866,0.0004750818,0.02782276,0.002045778,0.00003409363,0.9010121,0.0006446633,0.0196399,0.0008907738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944032,0.0008785356,0.003690528,0.0006799842,0.00007605247,0.0001663302,0.00001687007,0.000005646586,0.00008287965],"genre_scores_gemma":[0.9949119,0.0002283071,0.004199162,0.0001641669,0.0003882624,0.00001399362,0.000003899684,0.00002349207,0.00006682782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08985212,"threshold_uncertainty_score":0.5694382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009716740265513446,"score_gpt":0.244376250415466,"score_spread":0.2346595101499526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}