{"id":"W2781706026","doi":"10.1016/j.ygeno.2017.12.006","title":"DMRFusion: A differentially methylated region detection tool based on the ranked fusion method","year":2018,"lang":"en","type":"article","venue":"Genomics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"Division of Materials Research; Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic","keywords":"Biology; DNA methylation; Differentially methylated regions; Methylation; CpG site; Epigenetics; Bisulfite sequencing; Computational biology; Illumina Methylation Assay; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004948674,0.0001673118,0.0001188988,0.00005526213,0.000281514,0.00004220183,0.0001799646,0.000208012,0.00004615885],"category_scores_gemma":[0.0001286984,0.0001242728,0.0001108906,0.0001263495,0.00006127384,0.000002099562,0.00008022552,0.0001061017,0.00002455215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003198945,"about_ca_system_score_gemma":0.00005504341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001682998,"about_ca_topic_score_gemma":0.00004760877,"domain_scores_codex":[0.9988251,0.0002489497,0.0002229222,0.0003598205,0.0001417247,0.0002015079],"domain_scores_gemma":[0.9990965,0.00004900901,0.0001246417,0.0005396998,0.0001426383,0.0000475477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002891737,0.00003213727,0.00005887099,0.00000339914,0.00002225306,6.847771e-7,0.00004636444,0.0002811472,0.9604448,0.00005174521,0.00007258153,0.03869683],"study_design_scores_gemma":[0.0005325583,0.000578433,0.001718348,0.000007032465,0.00003092397,0.000001820652,0.00001606047,0.01900805,0.9526303,0.0005843568,0.02470933,0.0001827311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6910142,0.0001011245,0.3072959,0.0002670996,0.0003082599,0.0002480931,0.000003727894,0.00001588535,0.0007456943],"genre_scores_gemma":[0.9944885,0.0001179201,0.003973195,0.0005083666,0.0005834732,0.00002094249,0.00005746779,0.00003098449,0.0002191628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3034742,"threshold_uncertainty_score":0.5067698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0155550020039549,"score_gpt":0.2547812595504,"score_spread":0.2392262575464451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}